Valine dehydrogenase (NAD+)

Valine dehydrogenase (NAD+)
Identifiers
EC number 1.4.1.23
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Valine dehydrogenase (NAD+) (EC 1.4.1.23) is an enzyme with systematic name L-valine:NAD+ oxidoreductase (deaminating).[1][2] This enzyme catalyses the following chemical reaction

L-valine + H2O + NAD+ \rightleftharpoons 3-methyl-2-oxobutanoate + NH3 + NADH + H+

The enzyme from Streptomyces spp. has no activity with NADP+.

See also

References

  1. ↑ Vancurová, I., Vancura, A., Volc, J., Neuzil, J., Flieger, M., Basarová, G. and Behal, V. (1988). "Isolation and characterization of valine dehydrogenase from Streptomyces aureofaciens". J. Bacteriol. 170 (11): 5192–5196. PMC 211589. PMID 3182727.
  2. ↑ Navarrete, R.M., Vara, J.A. and Hutchinson, C.R. (1990). "Purification of an inducible L-valine dehydrogenase of Streptomyces coelicolor A3(2)". J. Gen. Microbiol. 136 (2): 273–281. doi:10.1099/00221287-136-2-273. PMID 2324704.

External links

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