Versatile peroxidase

Versatile peroxidase
Identifiers
EC number	1.11.1.16
CAS number	114995-15-2&title= 42613-30-9, 114995-15-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Versatile peroxidase (EC 1.11.1.16, VP, hybrid peroxidase, polyvalent peroxidase) is an enzyme with systematic name reactive-black-5:hydrogen-peroxide oxidoreductase.^{[1][2][3][4][5][6][7][8][9][10]} This enzyme catalyses the following chemical reaction

(1) Reactive Black 5 + H₂O₂ $\rightleftharpoons$ oxidized Reactive Black 5 + 2 H₂O

(2) donor + H₂O₂ $\rightleftharpoons$ oxidized donor + 2 H₂O

Versatile peroxidase is a hemoprotein.

References

1. Martínez, M.J., Ruiz-Dueñas, F.J., Guillén, F. and Martínez, A.T. (1996). "Purification and catalytic properties of two manganese peroxidase isoenzymes from Pleurotus eryngii". Eur. J. Biochem. 237 (2): 424–432. doi:10.1111/j.1432-1033.1996.0424k.x. PMID 8647081.
2. Heinfling, A., Ruiz-Dueñas, F.J., Martínez, M.J., Bergbauer, M., Szewzyk, U. and Martínez, A.T. (1998). "A study on reducing substrates of manganese-oxidizing peroxidases from Pleurotus eryngii and Bjerkandera adusta". FEBS Lett. 428 (3): 141–146. doi:10.1016/s0014-5793(98)00512-2. PMID 9654123.
3. Ruiz-Dueñas, F.J., Martínez, M.J. and Martínez, A.T. (1999). "Molecular characterization of a novel peroxidase isolated from the ligninolytic fungus Pleurotus eryngii". Mol. Microbiol. 31 (1): 223–235. doi:10.1046/j.1365-2958.1999.01164.x. PMID 9987124.
4. Camarero, S., Sarkar, S., Ruiz-Dueñas, F.J., Martínez, M.J. and Martínez, A.T. (1999). "Description of a versatile peroxidase involved in the natural degradation of lignin that has both manganese peroxidase and lignin peroxidase substrate interaction sites". J. Biol. Chem. 274 (15): 10324–10330. doi:10.1074/jbc.274.15.10324. PMID 10187820.
5. Ruiz-Dueñas, F.J., Martínez, M.J. and Martínez, A.T. (1999). "Heterologous expression of Pleurotus eryngii peroxidase confirms its ability to oxidize Mn²⁺ and different aromatic substrates". Appl. Environ. Microbiol. 65 (10): 4705–4707. PMC 91631. PMID 10508113.
6. Camarero, S., Ruiz-Dueñas, F.J., Sarkar, S., Martínez, M.J. and Martínez, A.T. (2000). "The cloning of a new peroxidase found in lignocellulose cultures of Pleurotus eryngii and sequence comparison with other fungal peroxidases". FEMS Microbiol. Lett. 191 (1): 37–43. doi:10.1016/s0378-1097(00)00367-0. PMID 11004397.
7. Ruiz-Dueñas, F.J., Camarero, S., Pérez-Boada, M., Martínez, M.J. and Martínez, A.T. (2001). "A new versatile peroxidase from Pleurotus". Biochem. Soc. Trans. 29 (Pt 2): 116–122. doi:10.1042/0300-5127:0290116. PMID 11356138.
8. Banci, L., Camarero, S., Martínez, A.T., Martínez, M.J., Pérez-Boada, M., Pierattelli, R. and Ruiz-Dueñas, F.J. (2003). "NMR study of manganese(II) binding by a new versatile peroxidase from the white-rot fungus Pleurotus eryngii". J. Biol. Inorg. Chem. 8 (7): 751–760. doi:10.1007/s00775-003-0476-1. PMID 12884090.
9. Pérez-Boada, M., Ruiz-Dueñas, F.J., Pogni, R., Basosi, R., Choinowski, T., Martínez, M.J., Piontek, K. and Martínez, A.T. (2005). "Versatile peroxidase oxidation of high redox potential aromatic compounds: site-directed mutagenesis, spectroscopic and crystallographic investigation of three long-range electron transfer pathways". J. Mol. Biol. 354 (2): 385–402. doi:10.1016/j.jmb.2005.09.047. PMID 16246366.
10. Caramelo, L., Martínez, M.J. and Martínez, A.T. (1999). "A search for ligninolytic peroxidases in the fungus Pleurotus eryngii involving α-keto-γ-thiomethylbutyric acid and lignin model dimer". Appl. Environ. Microbiol. 65 (3): 916–922. PMC 91123. PMID 10049842.

External links

• Versatile peroxidase at the US National Library of Medicine Medical Subject Headings (MeSH)