Xi River virus
Xi River virus | |
---|---|
Virus classification | |
Group: | Group III (dsRNA) |
Order: | Unassigned |
Family: | Reoviridae |
Subfamily: | Spinareovirinae |
Genus: | Orthoreovirus |
Type species | |
Pteropine orthoreovirus | |
Species | |
Xi River virus |
Xi River virus, (XRV), is a putative novel bat virus in the genus Orthoreovirus isolated from fruit bats in Guangdong Province in southern China. It is the first bat reovirus isolated in China.[1][2]
Virology
Genome
Only a partial sequence of XRV was isolated from the fruit bat, but based on its open reading frame it was identified as a reovirus.[1] XRV has the same morphology and high sequence identity as Nelson Bay virus (NBV), and a 10-segmented double-stranded RNA genome, as well as high sequence identity to NBV members.[3][4]
Reoviruses are non-enveloped, double-stranded RNA viruses. They have an icosahedral capsid (T-13) composed of an outer and inner protein shell. The genome contains 10–12 segments grouped into three categories by size: L (large), M (medium) and S (small). Segments range from ~ 3.9 kbp – 1kbp and each segment encodes 1–3 proteins. Reoviridae proteins are denoted by the Greek character corresponding to the segment it was translated from (the L segment encodes for λ proteins, the M segment encodes for μ proteins and the S segment encodes for σ proteins).[3][4]
See also
References
- 1 2 Du, L; Lu, Z; Fan, Y; Meng, K; Jiang, Y; Zhu, Y; Wang, S; Gu, W; Zou, X; Tu, C (Aug 2010). "Xi River virus, a new bat reovirus isolated in southern China". Arch Virol 155 (8): 1295–9. doi:10.1007/s00705-010-0690-4.
- ↑ "Seroprevalence of Rabies Virus Antibodies in Bats from Southern China". Vector-Borne and Zoonotic Diseases 10: 177–181. doi:10.1089/vbz.2008.0212.
- 1 2 MicrobiologyBytes – Reoviruses
External links
- Translation and Open Reading Frames
- NCBI ORF finder – A web based interactive tool for predicting and analysing ORFs from nucleotide sequences.