Broxyquinoline

Broxyquinoline
Systematic (IUPAC) name


5,7-Dibromoquinolin-8-ol
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	521-74-4^Y
ATC code	A07AX01 (WHO) G01AC06 P01AA01
PubChem	CID 2453
ChemSpider	2359^N
UNII	UK4C618C8T^Y
ChEMBL	CHEMBL223448^N
Chemical data
Formula	C₉H₅Br₂NO
Molar mass	302.95 g/mol
SMILES Brc1c(O)c2ncccc2c(Br)c1
InChI InChI=1S/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H^N Key:ZDASUJMDVPTNTF-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Broxyquinoline is an antiprotozoal agent.

An association with exercise intolerance has been reported.^[1]

References

↑ Swain R, Bapna JS (January 1986). "Impairment of exercise tolerance due to broxyquinoline-brobenzoxaldine combination". Hum Toxicol 5 (1): 63–4. doi:10.1177/096032718600500115. PMID 3081430.

Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07)

Rehydration	Oral rehydration therapy

Intestinal anti-infectives	Antibiotics Amphotericin B Colistin Fidaxomicin Kanamycin Natamycin Neomycin Nystatin Paromomycin Polymyxin B Rifaximin Streptomycin Vancomycin Sulfonamides Phthalylsulfathiazole Succinylsulfathiazole Sulfaguanidine Nitrofuran Nifuroxazide Nifurzide) Imidazole Miconazole Arsenical Acetarsol Oxyquinoline Broxyquinoline

Intestinal adsorbents	Charcoal Bismuth Pectin Kaolin Crospovidone Attapulgite Diosmectite

Antipropulsives (opioids)	Opium tincture (laudanum) Codeine Morphine Camphorated opium tincture (paregoric) crosses BBB: Diphenoxylate (Diphenoxylate/atropine) Difenoxin does not cross BBB: Eluxadoline Loperamide

Intestinal anti-inflammatory agents	corticosteroids acting locally Prednisolone Hydrocortisone Prednisone Betamethasone Tixocortol Budesonide Beclometasone antiallergic agents, excluding corticosteroids Cromoglicic acid aminosalicylic acid and similar agents Sulfasalazine Mesalazine Olsalazine Balsalazide

Antidiarrheal micro-organisms	Saccharomyces boulardii

Other antidiarrheals	Albumin tannate Ceratonia Crofelemer Octreotide Racecadotril

Antiparasitics – antiprotozoal agents – agents against amoebozoa/amebicide (P01)

Entamoeba

Tissue amebicides

Nitroimidazole derivatives	Metronidazole^# Tinidazole Ornidazole Nimorazole Secnidazole Azanidazole Propenidazole

Other	isoquinoline (Emetine/Dehydroemetine)

Luminal amebicides

Hydroxyquinoline derivatives	Cl (Chlorquinaldol) Br (Tilbroquinol Broxyquinoline) I (Diiodohydroxyquinoline) I, Cl (Clioquinol) related: Chiniofon

Dichloroacetamide derivatives	Diloxanide^# Clefamide Etofamide Teclozan

Aminoglycoside	Paromomycin

Other/ungrouped

Acanthamoeba

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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