Acetarsol

Acetarsol

Names
Preferred IUPAC name Acetarsone
Systematic IUPAC name (3-Acetamido-4-hydroxyphenyl)arsonic acid[1]
Other names 3-Acetamido-4-hydroxyphenylarsonic acid
Identifiers
CAS Number	97-44-9
ChEMBL	ChEMBL1330792
ChemSpider	1908
EC Number	202-582-3
Jmol 3D model	Interactive image Interactive image
KEGG	D07110
MeSH	Acetarsol
PubChem	1985
UNII	806529YU1N
UN number	3465
InChI InChI=1S/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15) Key: ODFJOVXVLFUVNQ-UHFFFAOYSA-N InChI=1/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15) Key: ODFJOVXVLFUVNQ-UHFFFAOYAX
SMILES CC(=O)Nc1cc(ccc1O)[As](O)(O)=O CC(=O)NC1=CC(=CC=C1O)[As](O)(O)=O
Properties
Chemical formula	C8H10AsNO5
Molar mass	275.0903 g mol^−1
Pharmacology
ATC code	A07AX02 (WHO) G01AB01 (WHO), P01CD02 (WHO), P51AD05 (WHO)
Hazards
GHS pictograms
GHS signal word	Danger
GHS hazard statements	H301, H331, H410
GHS precautionary statements	P261, P273, P301+310, P311, P501
EU classification (DSD)	T N
R-phrases	R23/25, R50/53
S-phrases	S20/21, S28, S45, S60, S61
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Acetarsol is an anti-infective.^[2]

It was first discovered in 1921 at Pasteur Institute by Ernest Fourneau, and sold under the brand name Stovarsol (fourneau is the French word for stove).^[3][4]

It has been given in suppositories.^[5]

References

1. "acetarsol - PubChem Public Chemical Database". The PubChem Project. USA: National Center for Biotechnology Information.
2. Chen MY, Smith NA, Fox EF, Bingham JS, Barlow D (April 1999). "Acetarsol pessaries in the treatment of metronidazole resistant Trichomonas vaginalis". Int J STD AIDS 10 (4): 277–80. doi:10.1258/0956462991913943. PMID 12035784.
3. Éric Fouassier, Ces poisons qui guérissent, oct. 1996, p. 5.
4. Traité de chimie organique, sous la direction de Victor Grignard, Paul Baud, vol. 22, Masson, 1959, p. 1127-1130.
5. Gionchetti P, Rizzello F, Morselli C, Campieri M (October 2004). "Review article: problematic proctitis and distal colitis". Aliment. Pharmacol. Ther. 20 Suppl 4: 93–6. doi:10.1111/j.1365-2036.2004.02049.x. PMID 15352902.