Chlorproguanil

Chlorproguanil
Names

IUPAC name 1-[Amino-(3,4-dichloroanilino)methylidene]-2-propan-2-ylguanidine
Identifiers
CAS Number	537-21-3^Y
ChemSpider	20950^N
Jmol interactive 3D	Image
PubChem	22323
UNII	8O3249M729^Y
InChI InChI=1S/C11H15Cl2N5/c1-6(2)16-10(14)18-11(15)17-7-3-4-8(12)9(13)5-7/h3-6H,1-2H3,(H5,14,15,16,17,18)^N Key: ISZNZKHCRKXXAU-UHFFFAOYSA-N^N InChI=1/C11H15Cl2N5/c1-6(2)16-10(14)18-11(15)17-7-3-4-8(12)9(13)5-7/h3-6H,1-2H3,(H5,14,15,16,17,18) Key: ISZNZKHCRKXXAU-UHFFFAOYAU
SMILES Clc1ccc(NC(=N/C(=N/C(C)C)N)N)cc1Cl
Properties
Chemical formula	C₁₁H₁₅Cl₂N₅
Molar mass	288.18 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Chlorproguanil is an antimalarial drug.

See also

Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)

Conoidasida/
(Coccidiostats)

Cryptosporidiosis	thiazolide (nitazoxanide)

Isosporiasis	trimethoprim/sulfamethoxazole^#

Toxoplasmosis	pyrimethamine sulfadiazine

Individual
agents

Hemozoin
inhibitors

aminoquinolines	(4-): amodiaquine^# chloroquine^# Tafenoquine (8-): primaquine^# pamaquine

4-methanolquinolines	mefloquine^# quinine^# quinidine

Other	lumefantrine combined with artemether halofantrine

DHFR inhibitors (antifols)	pyrimethamine proguanil^# chlorproguanil biguanides

Sulfonamides	sulfadoxine sulfamethoxypyrazine

Coformulation	sulfadoxine/pyrimethamine (SP)^#

Sesquiterpene
lactones

Other

Combi-
nations

Fixed-dose (coformulated) ACTs	artemether/lumefantrine^# artesunate/amodiaquine (ASAQ) artesunate/mefloquine (ASMQ) dihydroartemisinin/piperaquine artesunate/pyronaridine

Other combinations (not co-formulated)	artesunate/SP artesunate/mefloquine quinine/tetracycline quinine/doxycycline quinine/clindamycin

clindamycin

Balantidiasis: Tetracycline

Blastocystosis: Metronidazole

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

This article is issued from Wikipedia - version of the Wednesday, July 08, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.