Cafaminol

Cafaminol
Systematic (IUPAC) name


8-[(2-hydroxyethyl)(methyl)amino]-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione
Clinical data
Routes of administration	?
Legal status	℞ (Prescription only)
Identifiers
CAS Number	30924-31-3
ATC code	none
PubChem	CID 35685
ChemSpider	32824
UNII	0L1S25NC1L^Y
ChEMBL	CHEMBL2104570
Synonyms	Methylcoffanolamine; 8-(2-hydroxyethyl)methylaminocaffeine
Chemical data
Formula	C₁₁H₁₇N₅O₃
Molar mass	267.28 g/mol
SMILES O=C2N(c1nc(n(c1C(=O)N2C)C)N(CCO)C)C
InChI InChI=1S/C11H17N5O3/c1-13(5-6-17)10-12-8-7(14(10)2)9(18)16(4)11(19)15(8)3/h17H,5-6H2,1-4H3 Key:ZGNRRVAPHPANFI-UHFFFAOYSA-N

Cafaminol (Rhinetten, Rhinoptil) is a vasoconstrictor of the xanthine class used as a nasal decongestant in Germany.^[1]^[2]

References

↑ Rogowski M, Chodynicki S (October 1985). "[Use of the preparation Cafaminol in the treatment of acute rhinitis]". Wiadomości Lekarskie (Warsaw, Poland : 1960) (in Polish) 38 (20): 1437–40. PMID 3913153.
↑ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0.

Decongestants and other nasal preparations (R01)

Topical

Sympathomimetics, plain	Cyclopentamine Ephedrine Epinephrine Fenoxazoline Levomethamphetamine Metizoline Naphazoline Oxymetazoline Phenylephrine Propylhexedrine Tetryzoline Tramazoline Tuaminoheptane Tymazoline Xylometazoline

Antiallergic agents, excluding corticosteroids	Spaglumic acid histamine antagonists (Levocabastine Antazoline Thonzylamine) mast cell stabilizer (some are also antihistamines) (Cromoglicic acid Nedocromil Azelastine Olopatadine Lodoxamide)

Corticosteroids	Beclometasone dipropionate Betamethasone Budesonide Ciclesonide Dexamethasone Flunisolide Fluticasone Mometasone furoate Prednisolone Tixocortol Triamcinolone

Other nasal preparations	Cafaminol Calcium hexamine thiocyanate Eucalyptus oil Framycetin Hexamidine Hyaluronan Ipratropium bromide Mupirocin Retinol Ritiometan Saline water

Systemic use:
Sympathomimetics

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