Hexamidine

Hexamidine
Names


IUPAC name 4,4'-[hexane-1,6-diylbis(oxy)]dibenzenecarboximidamide
Other names 4-[6-(4-carbamimidoylphenoxy)hexoxy]benzamidine
Identifiers
CAS Number	3811-75-4^Y
ChEBI	CHEBI:87184^Y
ChEMBL	ChEMBL25105^Y
ChemSpider	58639^Y
DrugBank	DB03808^Y
Jmol interactive 3D	Image
PubChem	65130
UNII	3483C2H13H^Y
InChI InChI=1S/C20H26N4O2/c21-19(22)15-5-9-17(10-6-15)25-13-3-1-2-4-14-26-18-11-7-16(8-12-18)20(23)24/h5-12H,1-4,13-14H2,(H3,21,22)(H3,23,24)^Y Key: OQLKNTOKMBVBKV-UHFFFAOYSA-N^Y InChI=1/C20H26N4O2/c21-19(22)15-5-9-17(10-6-15)25-13-3-1-2-4-14-26-18-11-7-16(8-12-18)20(23)24/h5-12H,1-4,13-14H2,(H3,21,22)(H3,23,24) Key: OQLKNTOKMBVBKV-UHFFFAOYAW
SMILES O(c1ccc(cc1)C(=[N@H])N)CCCCCCOc2ccc(C(=[N@H])N)cc2
Properties
Chemical formula	C₂₀H₂₆N₄O₂
Molar mass	354.446
Pharmacology
ATC code	D08AC04 R01AX07 R02AA18 S01AX08 S03AA05
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is ^YN ?)
Infobox references

Hexamidine is an antiseptic and disinfectant. Hexomedine is the trade name of a diisethionate solution (1/1.000) of hexamidine.^[1]

References

↑ "Final Report on the Safety Assessment of Hexamidine and Hexamidine Diisethionate". International Journal of Toxicology 26: 79–88. 2007. doi:10.1080/10915810701663168. PMID 18273451.

Antiseptics and disinfectants (D08)

Acridine derivatives	Ethacridine lactate 9-Aminoacridine Euflavine

Biguanides and amidines	Dibrompropamidine Chlorhexidine^# Propamidine Hexamidine Polihexanide

Phenol and derivatives	Hexachlorophene Policresulen Phenol Triclosan Chloroxylenol^# Biphenylol Fenticlor

Nitrofuran derivatives	Nitrofurazone

Iodine products	Iodine/octylphenoxypolyglycolether Povidone-iodine^# Diiodohydroxypropane

Quinoline derivatives	Dequalinium Chlorquinaldol Oxyquinoline Clioquinol

Quaternary ammonium compounds	Benzalkonium Benzethonium chloride Cetrimonium (bromide/chloride) Cetylpyridinium Cetrimide Benzoxonium chloride Didecyldimethylammonium chloride

Mercurial products	Mercuric amidochloride Phenylmercuric borate Mercuric chloride Merbromin Thiomersal Mercuric iodide

Silver compounds	Silver nitrate

Alcohols	Propanol (propyl alcohol) Isopropanol (isopropyl alcohol) Ethanol (ethyl alcohol)^#

Other	Potassium permanganate Sodium hypochlorite Hydrogen peroxide Eosin Tosylchloramide Octenidine dihydrochloride

^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

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