Dibrompropamidine

Dibrompropamidine
Names

IUPAC name 3-bromo-4-[3-(2-bromo-4-carbamimidoylphenoxy)propoxy]benzamidine
Identifiers
CAS Number	496-00-4^Y
ChEMBL	ChEMBL30044^Y
ChemSpider	11479^Y
Jmol interactive 3D	Image Image
KEGG	D07204^Y
PubChem	11974
UNII	269M3QL74S^Y
InChI InChI=1S/C17H18Br2N4O2/c18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19/h2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23)^Y Key: GMJFVGRUYJHMCO-UHFFFAOYSA-N^Y InChI=1/C17H18Br2N4O2/c18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19/h2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23) Key: GMJFVGRUYJHMCO-UHFFFAOYAF
SMILES C1=CC(=C(C=C1C(=N)N)Br)OCCCOC2=C(C=C(C=C2)C(=N)N)Br Brc2cc(ccc2OCCCOc1ccc(C(=[N@H])N)cc1Br)C(=[N@H])N
Properties
Chemical formula	C₁₇H₁₈Br₂N₄O₂
Molar mass	470.16 g/mol
Pharmacology
ATC code	D08AC01 S01AX14
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is ^YN ?)
Infobox references

Dibrompropamidine is an antiseptic and disinfectant. As dibrompropamidine isethionate, it is used in eyedrops and ointment for the treatment of minor eye and eyelid infections in adults and children. In the UK, such preparations are sold under the brand names Brolene (Aventis Pharma), Golden Eye (Typharm Ltd) and Brulidine (Manx Healthcare).

Characteristics

A white or almost white, crystalline powder; odourless or almost odourless.

Freely soluble in water ; soluble in glycerol ; sparingly soluble in ethanol (96%); practically insoluble in chloroform, in ether, in liquid paraffin and in fixed oils.

Antiseptics and disinfectants (D08)

Acridine derivatives	Ethacridine lactate 9-Aminoacridine Euflavine

Biguanides and amidines	Dibrompropamidine Chlorhexidine^# Propamidine Hexamidine Polihexanide

Phenol and derivatives	Hexachlorophene Policresulen Phenol Triclosan Chloroxylenol^# Biphenylol Fenticlor

Nitrofuran derivatives	Nitrofurazone

Iodine products	Iodine/octylphenoxypolyglycolether Povidone-iodine^# Diiodohydroxypropane

Quinoline derivatives	Dequalinium Chlorquinaldol Oxyquinoline Clioquinol

Quaternary ammonium compounds	Benzalkonium Benzethonium chloride Cetrimonium (bromide/chloride) Cetylpyridinium Cetrimide Benzoxonium chloride Didecyldimethylammonium chloride

Mercurial products	Mercuric amidochloride Phenylmercuric borate Mercuric chloride Merbromin Thiomersal Mercuric iodide

Silver compounds	Silver nitrate

Alcohols	Propanol (propyl alcohol) Isopropanol (isopropyl alcohol) Ethanol (ethyl alcohol)^#

Other	Potassium permanganate Sodium hypochlorite Hydrogen peroxide Eosin Tosylchloramide Octenidine dihydrochloride

^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

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