Nitrofural

Nitrofural
Systematic (IUPAC) name


5-Nitro-2-furaldehyde semicarbazone
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Pregnancy category	US: C (Risk not ruled out)
Identifiers
CAS Number	59-87-0^Y
ATC code	B05CA03 (WHO) D08AF01 D09AA03 (dressing) P01CC02 S01AX04 S02AA02 QG01AX90 QP51AC02
PubChem	CID 5447130
DrugBank	DB00336^Y
ChemSpider	4566720^Y
UNII	X8XI70B5Z6^Y
KEGG	C08042^N
ChEBI	CHEBI:44368
ChEMBL	CHEMBL869^Y
Chemical data
Formula	C₆H₆N₄O₄
Molar mass	198.14 g/mol
SMILES O=[N+]([O-])c1oc(/C=N/NC(=O)N)cc1
InChI InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+^Y Key:IAIWVQXQOWNYOU-FPYGCLRLSA-N^Y
^NY (what is this?) (verify)

Nitrofural (INN, trade name Furacin) is a bactericidal compound used as an antibiotic most commonly in the form of ointments. Its use in medicine has become less frequent as safer and more effective products have become available, and it has been discontinued in the US.^[1] The substance is pale yellow and crystalline.

Other names include nitrofurazone and furacilin.

References

↑ Drugs.com: Nitrofurazone (Topical route)

Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)

Alveo-
late

Apicom-
plexa

Conoidasida/
(Coccidiostats)

Cryptosporidiosis	thiazolide (nitazoxanide)

Isosporiasis	trimethoprim/sulfamethoxazole^#

Toxoplasmosis	pyrimethamine sulfadiazine

Aconoidasida

Malaria

Individual
agents

Hemozoin
inhibitors

aminoquinolines	(4-): amodiaquine^# chloroquine^# Tafenoquine (8-): primaquine^# pamaquine

4-methanolquinolines	mefloquine^# quinine^# quinidine

Other	lumefantrine combined with artemether halofantrine

Antifolates

DHFR inhibitors (antifols)	pyrimethamine proguanil^# chlorproguanil biguanides

Sulfonamides	sulfadoxine sulfamethoxypyrazine

Coformulation	sulfadoxine/pyrimethamine (SP)^#

Sesquiterpene
lactones

Other

Combi-
nations

Fixed-dose (coformulated) ACTs	artemether/lumefantrine^# artesunate/amodiaquine (ASAQ) artesunate/mefloquine (ASMQ) dihydroartemisinin/piperaquine artesunate/pyronaridine

Other combinations (not co-formulated)	artesunate/SP artesunate/mefloquine quinine/tetracycline quinine/doxycycline quinine/clindamycin

Babesiosis

clindamycin

Cilio-
phora

Balantidiasis: Tetracycline

Hetero-
kont

Blastocystosis: Metronidazole

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Drugs used for diseases of the ear (S02)

Infection	Acetic acid Aluminium acetotartrate Boric acid Chloramphenicol Chlorhexidine Ciprofloxacin Clioquinol Gentamicin Hydrogen peroxide Miconazole Neomycin Nitrofurazone Ofloxacin Polymyxin B Rifamycin Tetracycline

Corticosteroids	Betamethasone Dexamethasone Fluocinolone acetonide Hydrocortisone Prednisolone

Analgesics and anesthetics	Lidocaine Cocaine Phenazone

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