| Year |
Title |
Developer |
Setting |
Platform |
Notes |
| 1978 | Santa Paravia en Fiumaccio | George Blank | Historical | APPII, PET, TRS80 | First appeared in the December 1978 issue of SoftSide magazine for the Radio Shack TRS-80. |
| 1982 | Utopia | Don Daglow | Contemporary | AQUA, INT | |
| 1983 | Nobunaga's Ambition | Koei | Historical | AMI, DOS, GB, GEN, MSX, NES, PC88, PC98, SNES | First title in the series. |
| 1985 | Little Computer People | David Crane | Contemporary | AMI, APPII, C64, CPC, ST, ZX | |
| 1986 | Alter Ego | Peter J. Favaro | Contemporary | APPII, C64, DOS, MAC, iPhone | |
| 1989 | Populous | Bullfrog | Fantasy | AMI, ARC, DOS, DS, GB, GEN, MAC, PC98, PCE, SMS, SNES, ST, X68K | |
| 1990 | SimEarth: The Living Planet | Maxis | Nature | AMI, DUO, DOS, MAC, PCE, SCD, SNES, WIN, X68K | |
| 1990 | Powermonger | Bullfrog | Fantasy | AMI, DOS, GEN, MAC, PC98, SCD, SNES, ST | |
| 1990 | ActRaiser | Quintet | Fantasy | MOBI, SNES, VC | Hybrid with side-scrolling platform game. |
| 1991 | Populous II: Trials of the Olympian Gods | Bullfrog | Fantasy | AMI, DOS, GEN, MAC, PC98, SNES, ST | Sequel to Populous. |
| 1991 | Mega Lo Mania (also known as Tyrants: Fight Through Time) | Sensible | Fantasy | AMI, DOS, GEN, SNES, ST | |
| 1992 | SimLife: The Genetic Playground | Maxis | Nature | AMI, DOS, MAC, WIN3X | The player controls the evolution of creatures. |
| 1994 | Fortress | F1 | Fantasy | AMI | |
| 1996 | Afterlife | LucasArts | Fantasy | DOS, MAC, WIN9X | |
| 1996 | Creatures | Creature Labs | Fantasy | WIN, MAC | |
| 1997 | Dungeon Keeper | Bullfrog | Fantasy | DOS, WIN9X, WIN | First title in the series. |
| 1997 | Dungeon Keeper: The Deeper Dungeons | Bullfrog | Fantasy | WIN | Expansion to Dungeon Keeper. |
| 1997 | Evolution: The Game of Intelligent Life | Crossover | Nature | WIN | A simulation of species evolution. |
| 1998 | Creatures 2 | Creature Labs | Fantasy | WIN | Sequel to Creatures. |
| 1998 | Populous: The Beginning | Bullfrog | Fantasy | PS1, PSN, WIN | Sequel to Populous II: Trials of the Olympian Gods. |
| 1999 | Creatures 3 | Creature Labs | Fantasy | WIN, LIN | Sequel to Creatures. |
| 1999 | Doshin the Giant | Param, Nintendo | Fantasy | GCN, N64 | |
| 1999 | Dungeon Keeper 2 | Bullfrog | Fantasy | WIN | Sequel to Dungeon Keeper. |
| 2000 | Kyojin no Doshin Kaihō Sensen Chibikko Chikko Daishūgō | Param | Fantasy | N64 | Expansion to Doshin the Giant. |
| 2000 | Majesty: The Fantasy Kingdom Sim | Cyberlore | Fantasy | LIN, MAC, WIN | |
| 2001 | Black & White | Lionhead | Fantasy | MAC, WIN | First title in the series. |
| 2001 | Docking Station | Creature Labs | Fantasy | WIN, LIN | Sequel to Creatures |
| 2001 | Startopia | Mucky Foot Productions | Sci-Fi | WIN | A space station sim. |
| 2002 | Black & White: Creature Isle | Lionhead | Fantasy | MAC, WIN | Expansion to Black & White. |
| 2005 | Black & White 2 | Lionhead | Fantasy | OSX, WIN | Sequel to Black & White. |
| 2006 | Viva Piñata | Rare | Fantasy | WIN, X360 | A simulation where players manage a garden to attract and mate piñata animals. |
| 2006 | Black & White 2: Battle of the Gods | Lionhead | Fantasy | OSX, WIN | Expansion to Black & White 2. |
| 2008 | Spore | Maxis | Nature/Sci-Fi | OSX, WIN, iPhone | Simulates the life and evolution of species from a cell to a space civilization in a fictional galaxy. |
| 2009 | Majesty 2: The Fantasy Kingdom Sim | 1C:Ino-Co | Fantasy | OSX, WIN | Sequel to Majesty: The Fantasy Kingdom Sim. |
| 2011 | From Dust | Ubisoft, Eric Chahi | Nature | X360, WIN, PSN | Nature simulation game where players control and model nature in order to save a human tribe from extinction. |
| 2013 | Reus | Abbey Games | Nature/Fantasy | WIN | A 2D god game where the player controls nature giants to balance human progression. |
| 2014 | Godus | 22cans | Fantasy | WIN, OSX, iPhone, Android | Spiritual successor to Populous. |
| 2015 | War for the Overworld | Subterranean Games | Fantasy | WIN, OSX, LIN | Spiritual successor to Dungeon Keeper 2. |
