| Office | Name | Party | Date | Notes | 
|---|
| Prime Minister, First Lord of the Treasury
 and Leader of the House of Lords
 | The Earl of Aberdeen | Peelite | 19 December 1852 – 30 January 1855 |  | 
| Chancellor of the Exchequer | William Ewart Gladstone | Peelite | 30 December 1852 |  | 
| Parliamentary Secretary to the Treasury | William Goodenough Hayter | Whig | 5 January 1853 |  | 
| Financial Secretary to the Treasury | James Wilson | Whig | 5 January 1853 |  | 
| Junior Lords of the Treasury | Lord Alfred Hervey | Peelite | 1 January 1853 – 7 March 1855 |  | 
| Lord Elcho |  | 1 January 1853 – 7 March 1855 | 
| John Sadleir |  | 1 January 1853 – 6 March 1854 | 
| Chichester Fortescue |  | 6 March 1854 – 16 April 1855 | 
| Lord Chancellor | The Lord Cranworth | Whig | 28 December 1852 |  | 
| Lord President of the Council | The Earl Granville | Whig | 28 December 1852 |  | 
| Lord John Russell | Whig | 12 June 1854 | also Leader of the House of Commons | 
| Lord Privy Seal | The Duke of Argyll |  | 4 January 1853 |  | 
| Secretary of State for the Home Department | The Viscount Palmerston | Whig | 28 December 1852 |  | 
| Under-Secretary of State for the Home Department | Henry Fitzroy | Peelite | 28 December 1852 |  | 
| Secretary of State for Foreign Affairs | Lord John Russell | Whig | 28 December 1852 | also Leader of the House of Commons | 
| The Earl of Clarendon | Whig | 21 February 1853 | 
| Under-Secretary of State for Foreign Affairs | The Lord Wodehouse |  | 28 December 1852 |  | 
| Secretary of State for War and the Colonies | The Duke of Newcastle | Peelite | 28 December 1852 | department abolished 10 June 1854 | 
| Under-Secretary of State for War and the Colonies | Frederick Peel | Peelite | 28 December 1852 | 
| Secretary of State for War | The Duke of Newcastle | Peelite | 12 June 1854 |  | 
| Under-Secretary of State for War | Henry Roberts |  | 12 June 1854 |  | 
| Secretary of State for the Colonies | Sir George Grey, Bt | Whig | 12 June 1854 |  | 
| Under-Secretary of State for the Colonies | Frederick Peel | Whig | 12 June 1854 |  | 
| First Lord of the Admiralty | Sir James Graham, Bt | Peelite | 30 December 1852 |  | 
| First Secretary of the Admiralty | Ralph Bernal Osborne |  | 6 January 1853 |  | 
| Civil Lord of the Admiralty | William Francis Cowper | Whig | 30 December 1852 |  | 
| President of the Board of Control | Sir Charles Wood, Bt | Whig | 30 December 1852 |  | 
| Joint Secretaries to the Board of Control | Robert Lowe |  | 30 December 1852 |  | 
| Sir Thomas Redington |  | 30 December 1852 | (permanent) | 
| Chancellor of the Duchy of Lancaster | Edward Strutt | Radical | 3 January 1853 |  | 
| The Earl Granville | Whig | 21 June 1854 | 
| Minister without Portfolio | The Marquess of Lansdowne | Whig | 28 December 1852 – 21 February 1858 |  | 
| Lord John Russell | Whig | 26 February 1853 – 8 June 1854 | also Leader of the House of Commons | 
| Secretary at War | Sidney Herbert | Peelite | 30 December 1852 |  | 
| First Commissioner of Works | Sir William Molesworth, Bt | Radical | 5 January 1853 |  | 
| President of the Board of Health | Sir Benjamin Hall, Bt | Whig | 14 January 1854 |  | 
| Chief Secretary for Ireland | Sir John Young, Bt | Peelite | 6 January 1853 |  | 
| Lord Lieutenant of Ireland | The Earl of St Germans | Peelite | 5 January 1853 |  | 
| Master-General of the Ordnance | The Lord Raglan | non-party | 30 September 1852 | continued in office | 
| Lieutenant-General of the Ordnance | Sir Hew Dalrymple Ross | non-party | 6 May 1854 | 
| Surveyor-General of the Ordnance | Lauderdale Maule | Whig | 5 January 1853 | died 1 August 1854 | 
| Clerk of the Ordnance | William Monsell | Whig | 13 January 1853 |  | 
| Storekeeper of the Ordnance | Sir Thomas Hastings | non-party | 25 July 1845 | continued in office | 
| Paymaster-General | The Lord Stanley of Alderley | Whig | 5 January 1853 |  | 
| Postmaster-General | The Viscount Canning | Peelite | 5 January 1853 |  | 
| President of the Poor Law Board | Matthew Talbot Baines | Whig | 30 December 1852 |  | 
| Parliamentary Secretary to the Poor Law Board | Grenville Berkeley |  | 7 January 1853 |  | 
| President of the Board of Trade | Edward Cardwell | Peelite | 28 December 1852 |  | 
| Vice-President of the Board of Trade | The Lord Stanley of Alderley | Whig | 4 January 1853 |  | 
| Attorney General | Sir Alexander Cockburn, Bt | Whig | 28 December 1852 |  | 
| Solicitor General | Sir Richard Bethell |  | 28 December 1852 |  | 
| Judge Advocate General | Charles Pelham Villiers |  | 30 December 1852 |  | 
| Lord Advocate | James Moncreiff |  | 30 December 1852 |  | 
| Solicitor General for Scotland | Robert Handyside |  | 17 January 1853 |  | 
| James Craufurd |  | 16 November 1853 | 
| Thomas Mackenzie |  | 11 January 1855 | 
| Attorney General for Ireland | Abraham Brewster | Peelite | April 1853 |  | 
| Solicitor General for Ireland | William Keogh |  | April 1853 |  | 
| Lord Steward of the Household | The Duke of Norfolk | Whig | 4 January 1853 |  | 
| The Earl Spencer | Whig | 10 January 1854 | 
| Lord Chamberlain of the Household | The Marquess of Breadalbane | Whig | 15 January 1853 |  | 
| Vice-Chamberlain of the Household | Lord Ernest Bruce | Peelite | 30 December 1852 |  | 
| Master of the Horse | The Duke of Wellington |  | 21 January 1853 |  | 
| Treasurer of the Household | Earl of Mulgrave | Whig | 4 January 1853 |  | 
| Comptroller of the Household | Viscount Drumlanrig |  | 4 January 1853 |  | 
| Captain of the Gentlemen-at-Arms | The Lord Foley | Whig | 30 December 1852 |  | 
| Captain of the Yeomen of the Guard | The Viscount Sydney |  | 30 December 1852 |  | 
| Master of the Buckhounds | The Earl of Bessborough | Whig | 30 December 1852 |  | 
| Chief Equerry and Clerk Marshal | Lord Alfred Paget | Whig | 30 December 1852 |  | 
| Mistress of the Robes | The Duchess of Sutherland | Whig | 15 January 1853 |  | 
| Lords in Waiting | The Marquess of Ormonde | Whig | 11 January 1853 – 25 September 1854 |  | 
| The Earl Somers |  | 13 January 1853 – 22 February 1857 | 
| The Lord Camoys | Whig | 13 January 1853 – 21 February 1858 | 
| The Lord Elphinstone | Whig | 13 January 1853 – 1 October 1853 | 
| The Lord Rivers | Peelite | 13 January 1853 – 21 February 1858 | 
| The Lord Waterpark | Whig | 13 January 1853 – 21 February 1858 | 
| The Lord de Tabley |  | 13 January 1853 – 21 February 1858 | 
| The Earl of Listowel | Whig | 1 October 1853 – 21 February 1856 | 
| The Lord Dufferin and Clandeboye | Whig | 28 November 1854 – 21 February 1858 |