Thymidine triphosphate

Thymidine triphosphate

Names
IUPAC name [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
Other names dTTP, 2'-deoxythymidine triphosphate
Identifiers
CAS Number	365-08-2=
ChEMBL	ChEMBL363559
ChemSpider	58493=
IUPHAR/BPS	5505
Jmol 3D model	Interactive image
MeSH	thymidine+5'-triphosphate
PubChem	64968
SMILES CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
Properties
Chemical formula	C10H17N2O14P3
Molar mass	482.168
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Deoxythymidine triphosphate (dTTP) is one of the four nucleotide triphosphates that are used in the in vivo synthesis of DNA. Unlike the other deoxyribonucleotide triphosphates, thymidine triphosphate does not always contain the "deoxy" prefix in its name.^[1] The corresponding ribonucleoside triphosphate is called uridine triphosphate.

It can be used by DNA ligase to create overlapping "sticky ends" so that protruding ends of opened microbial plasmids may be closed up.

References

1. Coghill, Anne M.; Garson, Lorrin R., ed. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.