Dehydratase

Dehydratase is an enzyme that catalyzes the removal of oxygen and hydrogen from organic compounds in the form of water. This process is also known as dehydration reaction.

There are four classes of dehydratases:

1. Dehydratases acting on 3-hydroxyacyl-CoA esters (no cofactors)

2. Dehydratases acting on 2-hydroxyacyl-CoA esters (radical reaction, [4Fe-4S] cluster containing)

3. Dehydratases acting on 4-hydroxyacyl-CoA esters ([4Fe-4S] and FAD containing)

4. Dehydratases containing an [4Fe-4S] cluster as active site (aconitase, fumarase, serine dehydratase)

External links

Dehydratases at the US National Library of Medicine Medical Subject Headings (MeSH)

Carbon-oxygen lyases (EC 4.2) (primarily dehydratases)

4.2.1: Hydro-Lyases	Carbonic anhydrase Fumarase Aconitase Enolase Alpha Enolase 2 Enoyl-CoA hydratase/3-Hydroxyacyl ACP dehydrase Methylglutaconyl-CoA hydratase Tryptophan synthase Cystathionine beta synthase Porphobilinogen synthase 3-Isopropylmalate dehydratase Urocanase Uroporphyrinogen III synthase Nitrile hydratase

4.2.2: Acting on polysaccharides	Hyaluronate lyase

4.2.3: Acting on phosphates	Threonine synthase

4.2.99: Other	Carboxymethyloxysuccinate lyase

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