ERP44
| Endoplasmic reticulum protein 44 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | ERP44 ; PDIA10; TXNDC4 | ||||||||||||
| External IDs | OMIM: 609170 MGI: 1923549 HomoloGene: 12638 GeneCards: ERP44 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 23071 | 76299 | |||||||||||
| Ensembl | ENSG00000023318 | ENSMUSG00000028343 | |||||||||||
| UniProt | Q9BS26 | Q9D1Q6 | |||||||||||
| RefSeq (mRNA) | NM_015051 | NM_029572 | |||||||||||
| RefSeq (protein) | NP_055866 | NP_083848 | |||||||||||
| Location (UCSC) |
Chr 9: 99.98 – 100.1 Mb |
Chr 4: 48.19 – 48.28 Mb | |||||||||||
| PubMed search | |||||||||||||
Endoplasmic reticulum resident protein 44 (ERp44) also known as thioredoxin domain-containing protein 4 (TXNDC4) is a protein that in humans is encoded by the ERP44 gene.[1][2][3]
Interactions
TXNDC4 has been shown to interact with ERO1L.[1][3]
References
- 1 2 Anelli T, Alessio M, Mezghrani A, Simmen T, Talamo F, Bachi A, Sitia R (Feb 2002). "ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family". The EMBO Journal 21 (4): 835–44. doi:10.1093/emboj/21.4.835. PMC 125352. PMID 11847130.
- ↑ "Entrez Gene: TXNDC4 thioredoxin domain containing 4 (endoplasmic reticulum)".
- 1 2 Galligan JJ, Petersen DR (July 2012). "The human protein disulfide isomerase gene family". Human Genomics 6 (6): 6. doi:10.1186/1479-7364-6-6. PMC 3500226. PMID 23245351.
Further reading
- Anelli T, Ceppi S, Bergamelli L, Cortini M, Masciarelli S, Valetti C, Sitia R (Oct 2007). "Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis". The EMBO Journal 26 (19): 4177–88. doi:10.1038/sj.emboj.7601844. PMC 2230840. PMID 17805346.
- Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- Otsu M, Bertoli G, Fagioli C, Guerini-Rocco E, Nerini-Molteni S, Ruffato E, Sitia R (2006). "Dynamic retention of Ero1alpha and Ero1beta in the endoplasmic reticulum by interactions with PDI and ERp44". Antioxidants & Redox Signaling 8 (3-4): 274–82. doi:10.1089/ars.2006.8.274. PMID 16677073.
- Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, Wakamatsu A, Kimura K, Sakamoto K, Hatano N, Kawai Y, Ishii S, Saito K, Kojima S, Sugiyama T, Ono T, Okano K, Yoshikawa Y, Aotsuka S, Sasaki N, Hattori A, Okumura K, Nagai K, Sugano S, Isogai T (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Research 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Higo T, Hattori M, Nakamura T, Natsume T, Michikawa T, Mikoshiba K (Jan 2005). "Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44". Cell 120 (1): 85–98. doi:10.1016/j.cell.2004.11.048. PMID 15652484.
- Breuza L, Halbeisen R, Jenö P, Otte S, Barlowe C, Hong W, Hauri HP (Nov 2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". The Journal of Biological Chemistry 279 (45): 47242–53. doi:10.1074/jbc.M406644200. PMID 15308636.
- Anelli T, Alessio M, Bachi A, Bergamelli L, Bertoli G, Camerini S, Mezghrani A, Ruffato E, Simmen T, Sitia R (Oct 2003). "Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44". The EMBO Journal 22 (19): 5015–22. doi:10.1093/emboj/cdg491. PMC 204474. PMID 14517240.
- O'Neill EE, Brock CJ, von Kriegsheim AF, Pearce AC, Dwek RA, Watson SP, Hebestreit HF (Mar 2002). "Towards complete analysis of the platelet proteome". Proteomics 2 (3): 288–305. doi:10.1002/1615-9861(200203)2:3<288::AID-PROT288>3.0.CO;2-0. PMID 11921445.
- Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581.
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