Ethacizine
Systematic (IUPAC) name | |
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ethyl N-[10-[3-(diethylamino)propanoyl]phenothiazin-2-yl]carbamate | |
Clinical data | |
Trade names | Ethacizin |
AHFS/Drugs.com | International Drug Names |
Legal status | |
Pharmacokinetic data | |
Bioavailability | ~40% (oral)[1] |
Protein binding | 90% |
Metabolism | Extensive hepatic |
Biological half-life | 2.5 hours |
Identifiers | |
CAS Number | 33414-33-4 |
ATC code | C01BC09 |
PubChem | CID 107841 |
ChemSpider | 96982 |
UNII | FE5SPV1Z6G |
Chemical data | |
Formula | C22H27N3O3S |
Molar mass | 413.54 g/mol |
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Ethacizine (ethacyzine) is a class Ic antiarrhythmic agent, related to moracizine. It is used in Russia and some other CIS countries for the treatment of severe and/or refractory ventricular and supraventricular arrhythmias, especially those accompanied by organic heart disease. It is also indicated as a treatment of refractory tachycardia associated with Wolff–Parkinson–White syndrome.[1]
It is manufactured under the brand name Ethacizin (Этацизин) by Olainfarm.[2]
References
- 1 2 "Этацизин (Ethacyzin) Prescribing Information. VIDAL Drug Compendium" (in Russian). Retrieved 5 February 2014.
- ↑ "Этацизин—4DOKTOR.RU Drug Information Handbook" (in Russian). Retrieved 5 February 2014.
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