Encainide
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Systematic (IUPAC) name | |
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4-methoxy-N-[2-(1-methyl-2-piperidin-1-ylethyl)phenyl]benzamide | |
Clinical data | |
Trade names | Enkaid |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
MedlinePlus | a605040 |
Legal status |
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Identifiers | |
CAS Number |
66778-36-7 ![]() |
ATC code | C01BC08 (WHO) |
PubChem | CID 48041 |
DrugBank |
DB01228 ![]() |
ChemSpider |
43697 ![]() |
UNII |
SY3J0147NB ![]() |
KEGG |
D07894 ![]() |
ChEBI |
CHEBI:4788 ![]() |
ChEMBL |
CHEMBL315838 ![]() |
Chemical data | |
Formula | C22H28N2O2 |
Molar mass | 352.47 g/mol |
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Encainide (trade name Enkaid) is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects.[1]
Synthesis
See also
References
- ↑ Echt, D. S.; Liebson, P. R.; Mitchell, L. B.; Peters, R. W.; Obias-Manno, D.; Barker, A. H.; Arensberg, D.; Baker, A.; Friedman, L.; Greene, H. L.; Huther, M. L.; Richardson, D. W. (1991). "Mortality and Morbidity in Patients Receiving Encainide, Flecainide, or Placebo". New England Journal of Medicine 324 (12): 781–788. doi:10.1056/NEJM199103213241201. PMID 1900101.
- ↑ S.J. Dykstra, J.L. Minelli, DE 2210154 (1972).
- ↑ S.J. Dykstra, J.L. Minelli, U.S. Patent 3,931,195 (1976).
- ↑ Dykstra, Stanley J. (1973). "Lysergic acid and quinidine analogs. 2-(o-Acylaminophenethyl)piperidines". Journal of Medicinal Chemistry 16 (9): 1015–1020. doi:10.1021/jm00267a012. PMID 4745503.
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