Flavanonol

Flavanonol, numbering

The flavanonols (with two "o"s aka 3-hydroxyflavanone or 2,3-dihydroflavonol) are a class of flavonoids that use the 3-hydroxy-2,3-dihydro-2-phenylchromen-4-one (IUPAC name) backbone.

Some examples include:

• Taxifolin (or Dihydroquercetin)
• Aromadedrin (or Dihydrokaempferol)

Metabolism

• Flavanone 3-dioxygenase
• Flavonol synthase
• Dihydroflavonol 4-reductase

Glycosides

Glycosides (chrysandroside A and chrysandroside B) can be found in the roots of Gordonia chrysandra.^[1] Xeractinol, a dihydroflavonol C-glucoside, can be isolated from the leaves of Paepalanthus argenteus var. argenteus.^[2]

Dihydro-flavonol glycosides (astilbin, neoastilbin, isoastilbin, neoisoastilbin, (2R, 3R)-taxifolin-3'-O-beta-D-pyranoglucoside) have been identified in the rhizome of Smilax glabra.^[3]

References

1. Kun Wanga; Jing Zhi Yanga; Li Zuoa; Dong Ming Zhang (January 2008). "Two new flavanonol glycosides from Gordonia chrysandra". Chinese Chemical Letters 19 (1): 61–4. doi:10.1016/j.cclet.2007.10.033.
2. Anne Lígia Dokkedal; Francisco Lavarda; Lourdes Campaner dos Santos; Wagner Vilegas (March–April 2007). "Xeractinol – a new flavanonol C-glucoside from Paepalanthus argenteus var. argenteus (Bongard) Hensold (Eriocaulaceae)". J. Braz. Chem. Soc. 18 (2). doi:10.1590/S0103-50532007000200029.
3. Yuan JZ, Dou DQ, Chen YJ; et al. (September 2004). "[Studies on dihydroflavonol glycosides from rhizome of Smilax glabra]". Zhongguo Zhong Yao Za Zhi (in Chinese) 29 (9): 867–70. PMID 15575206.