| Goal | Date | Venue | Opponent | Score | Result | Competition |
| 1. | 1 March 2006 | St. Jakob-Park, Basel, Switzerland |  Croatia | 2–1 | 2–3 | Friendly |
| 2. | 16 June 2006 | Veltins-Arena, Gelsenkirchen, Germany |  Serbia and Montenegro | 6–0 | 6–0 | 2006 FIFA World Cup |
| 3. | 5 June 2007 | Camp Nou, Barcelona, Spain |  Algeria | 2–2 | 4–3 | Friendly |
| 4. | 5 June 2007 | Camp Nou, Barcelona, Spain | Algeria | 3–2 | 4–3 | Friendly |
| 5. | 8 July 2007 | Estadio Metropolitano de Fútbol de Lara, Barquisimeto, Venezuela |  Peru | 2–0 | 4–0 | 2007 Copa América |
| 6. | 11 July 2007 | Polideportivo Cachamay, Puerto Ordaz, Venezuela |  Mexico | 2–0 | 3–0 | 2007 Copa América |
| 7. | 16 October 2007 | Estadio José Pachencho Romero, Maracaibo, Venezuela |  Venezuela | 2–0 | 2–0 | 2010 FIFA World Cup qualifier |
| 8. | 20 November 2007 | Estadio El Campín, Bogotá, Colombia |  Colombia | 1–0 | 1–2 | 2010 FIFA World Cup qualifier |
| 9. | 4 June 2008 | Qualcomm Stadium, San Diego, United States | Mexico | 2–0 | 4–1 | Friendly |
| 10. | 11 October 2008 | Estadio Antonio V. Liberti, Buenos Aires, Argentina |  Uruguay | 1–0 | 2–1 | 2010 FIFA World Cup qualifier |
| 11. | 11 February 2009 | Stade Vélodrome, Marseille, France |  France | 2–0 | 2–0 | Friendly |
| 12. | 28 March 2009 | Estadio Antonio V. Liberti, Buenos Aires, Argentina | Venezuela | 1–0 | 4–0 | 2010 FIFA World Cup qualifier |
| 13. | 14 November 2009 | Vicente Calderón Stadium, Madrid, Spain |  Spain | 1–1 | 1–2 | Friendly |
| 14. | 7 September 2010 | Estadio Antonio V. Liberti, Buenos Aires, Argentina | Spain | 1–0 | 4–1 | Friendly |
| 15. | 17 November 2010 | Khalifa International Stadium, Doha, Qatar |  Brazil | 1–0 | 1–0 | Friendly |
| 16. | 9 February 2011 | Stade de Genève, Geneva, Switzerland |  Portugal | 2–1 | 2–1 | Friendly |
| 17. | 20 June 2011 | Estadio Antonio V. Liberti, Buenos Aires, Argentina |  Albania | 2–0 | 4–0 | Friendly |
| 18. | 7 October 2011 | Estadio Antonio V. Liberti, Buenos Aires, Argentina |  Chile | 2–0 | 4–1 | 2014 World Cup qualifier |
| 19. | 15 November 2011 | Estadio Metropolitano Roberto Meléndez, Barranquilla, Colombia | Colombia | 1–1 | 2–1 | 2014 FIFA World Cup qualifier |
| 20. | 29 February 2012 | Stade de Suisse Wankdorf, Bern, Switzerland |  Switzerland | 1–0 | 3–1 | Friendly |
| 21. | 29 February 2012 | Stade de Suisse Wankdorf, Bern, Switzerland | Switzerland | 2–1 | 3–1 | Friendly |
| 22. | 29 February 2012 | Stade de Suisse Wankdorf, Bern, Switzerland | Switzerland | 3–1 | 3–1 | Friendly |
| 23. | 2 June 2012 | Estadio Antonio V. Liberti, Buenos Aires, Argentina |  Ecuador | 3–0 | 4–0 | 2014 FIFA World Cup qualifier |
| 24. | 9 June 2012 | MetLife Stadium, East Rutherford, United States | Brazil | 1–1 | 4–3 | Friendly |
| 25. | 9 June 2012 | MetLife Stadium, East Rutherford, United States | Brazil | 2–1 | 4–3 | Friendly |
| 26. | 9 June 2012 | MetLife Stadium, East Rutherford, United States | Brazil | 4–3 | 4–3 | Friendly |
| 27. | 15 August 2012 | Commerzbank Arena, Frankfurt, Germany |  Germany | 2–1 | 3–1 | Friendly |
| 28. | 7 September 2012 | Estadio Mario Alberto Kempes, Córdoba, Argentina |  Paraguay | 3–1 | 3–1 | 2014 FIFA World Cup qualifier |
| 29. | 12 October 2012 | Estadio Malvinas Argentinas, Mendoza, Argentina | Uruguay | 1–0 | 3–0 | 2014 FIFA World Cup qualifier |
| 30. | 12 October 2012 | Estadio Malvinas Argentinas, Mendoza, Argentina | Uruguay | 3–0 | 3–0 | 2014 FIFA World Cup qualifier |
| 31. | 16 October 2012 | Estadio Nacional, Santiago, Chile | Chile | 1–0 | 2–1 | 2014 FIFA World Cup qualifier |
| 32. | 22 March 2013 | Estadio Antonio V. Liberti, Buenos Aires, Argentina | Venezuela | 3–0 | 3–0 | 2014 FIFA World Cup qualifier |
| 33. | 14 June 2013 | Estadio Mateo Flores, Guatemala City, Guatemala |  Guatemala | 1–0 | 4–0 | Friendly |
| 34. | 14 June 2013 | Estadio Mateo Flores, Guatemala City, Guatemala | Guatemala | 3–0 | 4–0 | Friendly |
| 35. | 14 June 2013 | Estadio Mateo Flores, Guatemala City, Guatemala | Guatemala | 4–0 | 4–0 | Friendly |
| 36. | 10 September 2013 | Estadio Defensores del Chaco, Asunción, Paraguay | Paraguay | 1–0 | 5–2 | 2014 FIFA World Cup qualifier |
| 37. | 10 September 2013 | Estadio Defensores del Chaco, Asunción, Paraguay | Paraguay | 4–1 | 5–2 | 2014 FIFA World Cup qualifier |
| 38. | 7 June 2014 | Estadio Ciudad de La Plata, La Plata, Argentina |  Slovenia | 2–0 | 2–0 | Friendly |
| 39. | 15 June 2014 | Estádio do Maracanã, Rio de Janeiro, Brazil |  Bosnia and Herzegovina | 2–0 | 2–1 | 2014 FIFA World Cup |
| 40. | 21 June 2014 | Estádio Mineirão, Belo Horizonte, Brazil |  Iran | 1–0 | 1–0 | 2014 FIFA World Cup |
| 41. | 25 June 2014 | Estádio Beira-Rio, Porto Alegre, Brazil |  Nigeria | 1–0 | 3–2 | 2014 FIFA World Cup |
| 42. | 25 June 2014 | Estádio Beira-Rio, Porto Alegre, Brazil | Nigeria | 2–1 | 3–2 | 2014 FIFA World Cup |
| 43. | 14 October 2014 | Hong Kong Stadium, So Kon Po, Hong Kong |  Hong Kong | 5–0 | 7–0 | Friendly |
| 44. | 14 October 2014 | Hong Kong Stadium, So Kon Po, Hong Kong | Hong Kong | 7–0 | 7–0 | Friendly |
| 45. | 12 November 2014 | Upton Park, London, United Kingdom | Croatia | 2–1 | 2–1 | Friendly |
| 46. | 13 June 2015 | Estadio La Portada, La Serena, Chile | Paraguay | 2–0 | 2–2 | 2015 Copa América |
| 47. | 4 September 2015 | BBVA Compass Stadium, Houston, United States |  Bolivia | 5–0 | 7–0 | Friendly |
| 48. | 4 September 2015 | BBVA Compass Stadium, Houston, United States | Bolivia | 6–0 | 7–0 | Friendly |
| 49. | 8 September 2015 | AT&T Stadium, Arlington, United States | Mexico | 2–2 | 2–2 | Friendly |
| 50. | 29 March 2016 | Estadio Mario Alberto Kempes, Córdoba, Argentina | Bolivia | 2–0 | 2–0 | 2018 FIFA World Cup qualifier |
