Lumiliximab

Lumiliximab
Monoclonal antibody
Type Whole antibody
Source Chimeric (primate/human)
Target CD23
Identifiers
ATC code None
ChemSpider none
UNII 8Z13S29R5A YesY
Chemical data
Formula C2115H3252N556O673S16
Molar mass 47.75 kg/mol
 NYesY (what is this?)  (verify)

Lumiliximab is a monoclonal antibody that targets CD23. It acts as an immunomodulator[1] and, as of October 2009, it is being investigated in Phase I and II clinical trials for the treatment of chronic lymphocytic leukemia.[2][3] The drug is a chimeric antibody from Macaca irus and Homo sapiens.[1]

References

  1. 1 2 International Nonproprietary Names for Pharmaceutical Substances (INN). World Health Organization.
  2. ↑ Byrd, J. C.; Kipps, T. J.; Flinn, I. W.; Castro, J.; Lin, T. S.; Wierda, W.; Heerema, N.; Woodworth, J.; Hughes, S.; Tangri, S.; Harris, S.; Wynne, D.; Molina, A.; Leigh, B.; O'Brien, S. (2009). "Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia". Blood 115 (3): 489–495. doi:10.1182/blood-2009-08-237727. PMC 2810983. PMID 19843887.
  3. ↑ Clinical trial number NCT00801060 at ClinicalTrials.gov


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