Persephin

persephin
Identifiers
Symbol	PSPN
Entrez	5623
HUGO	9579
OMIM	602921
RefSeq	NM_004158
UniProt	O60542
Other data
Locus	Chr. 19 p13.3

Persephin is a neurotrophic factor in the glial cell line-derived neurotrophic factor (GDNF) family.

External links

persephin at the US National Library of Medicine Medical Subject Headings (MeSH)

Cell signaling: Nervous tissue: Neurotrophic factors

Neurotrophins	NGF BDNF NT-3 NT-4

GDNF family	GDNF Artemin Neurturin Persephin

Ephrins	A1 A2 A3 A4 A5 B1 B2 B3

CNTF family	CNTF LIF IL-6

Other	GMF IGF-1 Neuregulins 1 2 3 4 PACAP VEGF

Neurotrophinergics

Agonists: Axokine
CNTF

Agonists: BDNF
NGF
NT-3
NT-4

Antagonists: SAR127963

GFRα1	Agonists: GDNF

GFRα2	Agonists: Neurturin (NRTN)

GFRα3	Agonists: Artemin (ARTN)

GFRα4	Agonists: Persephin (PSPN)

TrkA	Agonists: Amitriptyline Gambogic amide NGF Tavilermide Antagonists: FX007 Kinase inhibitors: K252a Lestaurtinib

TrkB	Agonists: 3,7-DHF 3,7,8,2'-THF 4'-DMA-7,8-DHF 7,3'-DHF 7,8-DHF 7,8,2'-THF 7,8,3'-THF Amitriptyline BDNF Deoxygedunin Diosmetin HIOC LM22A-4 N-Acetylserotonin NT-3 NT-4 Norwogonin (5,7,8-THF) R7 TDP6 Antagonists: ANA-12 Cyclotraxin B Gossypetin (3,5,7,8,3',4'-HHF) Kinase inhibitors: K252a Lestaurtinib

TrkC	Agonists: NT-3 Kinase inhibitors: K252a Lestaurtinib

Others

Antibodies: Tanezumab (against NGF)

Others: Cerebrolysin (neurotrophin mixture)

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