Prothionamide

Prothionamide

Systematic (IUPAC) name
2-propylpyridine-4-carbothioamide
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	14222-60-7
ATC code	J04AD01 (WHO)
PubChem	CID 666418
ChemSpider	579891
UNII	76YOO33643
Chemical data
Formula	C9H12N2S
Molar mass	180.271 g/mol
SMILES CCCc1cc(ccn1)C(=S)N
InChI InChI=1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) Key:VRDIULHPQTYCLN-UHFFFAOYSA-N
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Protionamide (or prothionamide) is a drug used in the treatment of tuberculosis.^[1]

It has also been tested for use in the treatment of leprosy.^[2]

See also

• Thioamide

References

1. Wang F, Langley R, Gulten G, et al. (January 2007). "Mechanism of thioamide drug action against tuberculosis and leprosy". J. Exp. Med. 204 (1): 73–8. doi:10.1084/jem.20062100. PMC 2118422. PMID 17227913.
2. Fajardo TT, Guinto RS, Cellona RV, Abalos RM, Dela Cruz EC, Gelber RH (March 2006). "A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy". Am. J. Trop. Med. Hyg. 74 (3): 457–61. PMID 16525107.