Haplogroup R1a1

Haplogroup R1a1
Possible place of origin Eurasia
Ancestor R-M448
Defining mutations M17, M198, M512, M514, M515, L168, L449, L457, L566

Haplogroup R1a1, also referred to as haplogroup R-M17 or R-M198, is a Y-DNA haplogroup defining one of the most common human male lines found in modern Eurasia. It is defined by the SNP mutation M17, and is particularly common in a large region extending from Central Europe and Scandinavia to South Asia and Southern Siberia.[1]

The R1a1 is the most common subclade within the family of the Y-DNA Haplogroup R1a. Before the discovery of M420, R1a1 was referred to as R1a. R1a shares in common the M420 SNP mutation, and haplogroup R-M420 is now referred to as R1a.

Origins

The modern distribution of R1a1 has two widely separated areas of high frequency: South Asia and Eastern Europe.

The question of the origins of R1a1 is therefore also relevant to an ongoing debate concerning the urheimat of the proto-Indo-European people.

Some researchers have claimed that South Asian populations had the highest STR diversity within R1a1.[2][3][1][4][5][6][7][8] Other studies have proposed Eastern European, Central Asian and even West Asian origins for R1a1.[1][9][2][10][11][10]

Coalescent time estimates for R-M17(xM458) STR from (Underhill 2009)
Location TD
W. India 15,800
Pakistan 15,000
Nepal 14,200
India 14,000
Oman 12,500
N. India 12,400
S. India 12,400
Caucasus 12,200
E. India 11,800
Poland 11,300
Slovakia 11,200
Crete 11,200
Germany 9,900
Denmark 9,700
UAE 9,700

Ancient DNA and archaeological correlates

Archaeologists recognize a complex of inter-related and relatively mobile cultures living on the Eurasian steppe, part of which protrudes into Europe as far west as Ukraine. These cultures from the late Neolithic and into the Iron Age, with specific traits such as Kurgan burials and horse domestication, have been associated with the dispersal of Indo-European languages across Eurasia. Nearly all samples from Bronze and Iron Age graves in the Krasnoyarsk area in south Siberia belonged to R1a1 and appeared to represent an eastward migration from Europe.[12] In central Europe, Corded Ware period human remains at Eulau from which Y-DNA was extracted appear to be R-M17(xM458) (which they found most similar to the modern German R-M17* haplotype.Underhill 2009

Frequency distribution of R1a1 adapted from (Underhill 2009).

Distribution

Asia

Central Asia

In Afghanistan, R1a1 is found at 51.02% among the Pashtuns who are the largest ethnic group in Afghanistan, 50% among the Kyrgyz and 30.36% among the Tajiks. It is less frequent among the Hazaras (6.67%) and the Turkic-speaking Uzbeks (17.65%) (Haber 2012).

South Asia

In South Asia, R1a1 has often been observed with high frequency in a number of demographic groups. (Sahoo 2006 and Sengupta 2005)

In India, high frequencies of this haplogroup is observed in West Bengal Brahmins (72%)(Sengupta 2005) to the east, Konkanastha Brahmins (48%) (Sengupta 2005) to the west, Khatris (67%)(Underhill 2009) in the north and Iyenger Brahmins (31%)(Sengupta 2005) in the south. It has also been found in several South Indian Dravidian-speaking Adivasis including the Chenchu (26%) and the Valmikis of Andhra Pradesh and the Kallar of Tamil Nadu suggesting that R1a1 is widespread in Tribal Southern Indians (Kivisild 2003).

Besides these, studies show high percentages in regionally diverse groups such as Manipuris (50%)(Underhill 2009) to the extreme North East and in Punjab (47%)(Kivisild 2003) to the extreme North West.

In Pakistan it is found at 71% among the Mohanna tribe in Sindh province to the south and 46% among the Baltis of Gilgit-Baltistan to the north (Underhill 2009). Among the Sinhalese of Sri Lanka, 23% were found to be R1a1a (R-SRY1532) positive in a sample size of 87 subjects.[13] Hindus of Terai region of Nepal show it at 69% (Fornarino 2009).

East Asia

The frequency of R1a1 is comparatively low among some Turkic-speaking groups including Turks, Azeris, Kazakhs, and Yakuts, yet levels are higher (19 to 28%) in certain Turkic or Mongolic-speaking groups of Northwestern China, such as the Bonan, Dongxiang, Salar, and Uyghurs.(Wells 2001, Wang 2003, and Zhou 2007)

In Eastern Siberia, R1a1 is found among certain indigenous ethnic groups including Kamchatkans and Chukotkans, and peaking in Itel'man at 22% (Lell 2002).

West Asia

R1a1 has been found in various forms, in most parts of Western Asia, in widely varying concentrations, from almost no presence in areas such as Jordan, to much higher levels in parts of Kuwait, Turkey and Iran. The Shimar (Shammar) Bedouin tribe in Kuwait show the highest frequency in the Middle East at 43%.(Mohammad 2009,Nasidze 2004, and Nasidze 2005)

Wells 2001, noted that in the western part of the country, Iranians show low R1a1 levels, while males of eastern parts of Iran carried up to 35% R1a1. Nasidze 2004 found R1a1 in approximately 20% of Iranian males from the cities of Tehran and Isfahan. Regueiro 2006 in a study of Iran, noted much higher frequencies in the south than the north.

A newer Study has found 20.3% R-M17* among Kurdish samples which were taken in the Kurdistan Province in western Iran, 9.7% among Mazandaranis in North Iran in the province of Mazandaran, 9.4% among Gilaks in province of Gilan, 12.8% among Persian and 17.6% among Zoroastrians in Yazd, 18.2% among Persians in Isfahan, 20.3% among Persians in Khorasan, 16.7% Afro-Iranians, 18.4% Qeshmi "Gheshmi", 21.4% among Persian Speaking Bandari people in Hormozgan and 25% among the Baloch people in Sistan and Baluchestan Province (Grugni 2012).

Further to the north of these Middle Eastern regions on the other hand, R1a1 levels start to increase in the Caucasus, once again in an uneven way. Several populations studied have shown no sign of R1a1, while highest levels so far discovered in the region appears to belong to speakers of the Karachay-Balkar language among whom about one quarter of men tested so far are in haplogroup R1a1 (Underhill 2009).

Europe

R1a1 among other European haplogroups

In Europe, the R1a1 sub-clade, is found at highest levels among peoples of Eastern European descent (Sorbs, Poles, Russians and Ukrainians; 50 to 65%) (Balanovsky 2008, Behar 2003, and Semino 2000). In the Baltic countries R1a1 frequencies decrease from Lithuania (45%) to Estonia (around 30%) (Kasperaviciūte 2005). Levels in Hungarians have been noted between 20 and 60% (Battaglia 2008, Rosser 2000, Semino 2000, and Tambets 2004).

There is a significant presence in peoples of Scandinavian descent, with highest levels in Norway and Iceland, where between 20 and 30% of men are in R1a1 (Bowden 2008 and (Dupuy 2005)). Vikings and Normans may have also carried the R1a1 lineage westward; accounting for at least part of the small presence in the British Isles (Passarino 2002 and Capelli 2003). In East Germany, where Haplogroup R1a1 reaches a peak frequency in Rostock at a percentage of 31.3%, it averages between 20%-30% (Kayser 2005).

Haplogroup R1a1 was found at elevated levels among a sample of the Israeli population who self-designated themselves as Levites and Ashkenazi Jews (Levites comprise approximately 4% of Jews). Behar reported R1a1 to be the dominant haplogroup in Ashkenazi Levites (52%), although rare in Ashkenazi Cohanim (1.3%). (Behar 2003).

In Southern Europe R1a1 is not common, but significant levels have been found in pockets, such as in the Pas Valley in Northern Spain, areas of Venice, and Calabria in Italy (Scozzari 2001). The Balkans shows lower frequencies, and significant variation between areas, for example >30% in Slovenia, Croatia and Greek Macedonia, but <10% in Albania, Kosovo and parts of Greece (Pericić 2005, Rosser 2000, and Semino 2000).

The remains of a father and his two sons, from an archaeological site discovered in 2005 near Eulau (in Saxony-Anhalt, Germany) and dated to about 2600 BCE, tested positive for the Y-SNP marker SRY10831.2. The Ysearch number for the Eulau remains is 2C46S. The ancestral clade was thus present in Europe at least 4600 years ago, in association with one site of the widespread Corded Ware culture (Haak 2008).

Subclade distribution

R-M458 This branch is found almost entirely in Europe, and with low frequency in Turkey and parts of the Caucasus. Its highest frequencies were found in Central and Southern Poland, particularly near the river valleys flowing northwards to the Baltic sea (Underhill 2009).

R-M334 was found only in one Estonian man and may define a very recently founded and small clade (Underhill 2009).

Relative frequency of R-M434 to R-M17
Region People N R-M17 R-M434
Number Freq. (%) Number Freq. (%)
 Pakistan Baloch60915%58%
 Pakistan Makrani601525% 47%
 Middle East Oman121119% 32.5%
 Pakistan Sindhi1346549% 21%
Table only shows positive sets from N = 3667 derived from 60 Eurasian populations sample, (Underhill 2009)


R-M87 (defined by the M64.2, M87, and M204 SNP mutations) is apparently rare: it was found in 1 of 117 males typed in southern Iran (Regueiro 2006).

R-M434 was detected in 14 people (out of 3667 people tested) all in a restricted geographical range from Pakistan to Oman. This likely reflects a recent mutation event in Pakistan (Underhill 2009).

Associated SNPs

SNP Mutation Y-position (NCBI36) Y-position (GRCh37) RefSNP ID
M17INS G2019255621733168rs3908
M198C->T1354014615030752rs2020857
M512C->T1482454716315153rs17222146
M514C->T1788468819375294rs17315926
M515T->A1256462314054623rs17221601
L168A->G1471157116202177-
L449C->T2137614422966756-
L457G->A1494626616436872rs113195541
L566C->T---

Subgroups

Thomas Krahn's draft tree

This is Thomas Krahn at the Genomic Research Center's Draft tree Proposed Tree for haplogroup R-M17.

R1a1 subclades and STR clusters

Frequency distribution of R-M458

R-M458

R-M458 is a mainly Slavic SNP, characterized by its own mutation, and was first called cluster N. Underhill et al. (2009) found it to be present in modern European populations roughly between the Rhine catchment and the Ural Mountains and traced it to "a founder effect that [...] falls into the early Holocene period, 7.9±2.6 KYA."(Underhill 2010) M458 was found in one skeleton from a 14th-century grave field in Usedom, Mecklenburg-Vorpommern, Germany.[14] The paper by Underhill et al. (2009) also reports a surprisingly high frequency of M458 in some Northern Caucasian populations (for example 27.5% among Karachays and 23.5% among Balkars, 7.8% among Karanogays and 3.4% among Abazas).

R-L260

The R-L260 lineage, commonly referred to as West Slavic or Polish, is a subclade of the larger parent group R-M458, and was first identified as an STR cluster by Pawlowski 2002 and then by Gwozdz 2009. Thus, R-L260 was what Gwozdz 2009 called cluster "P." In 2010 it was verified to be a haplogroup identified by its own mutation (SNP).[15] It apparently accounts for about 8% of Polish men, making it the most common subclade in Poland. Outside of Poland it is less common (Pawlowski 2002). In addition to Poland, it is mainly found in the Czech Republic and Slovakia, and is considered "clearly West Slavic."[16] The founding ancestor of R-L260 is estimated to have lived between 2000 and 3000 years ago, i.e. during the Iron Age, with significant population expansion less than 1,500 years ago (Gwozdz 2009).

R-M334

The R-M334 was identified in an Estonian population sample (Underhill 2009).

R-L365

R-L365 was early called Cluster G.

Gwozdz's Cluster K

This is an STR based group that is R-M17(xM458). This cluster is common in Poland but not exclusive to Poland (Gwozdz 2009).

See also

Y-DNA R-M207 Subclades

Y-DNA backbone tree

Evolutionary tree of human Y-chromosome DNA haplogroups [χ 1][χ 2]
"Y-chromosomal Adam"
A00 A0-T [χ 3]
A0 A1[χ 4]
A1a A1b
A1b1 BT
B CT
DE CF
D E C F
F1 F2 F3 GHIJK
G HIJK
H IJK
IJ K
I J LT [χ 5]  K2
L T NO [χ 6] K2b [χ 7]   K2c K2d K2e [χ 8]
N O K2b1 [χ 9]    P
M S [χ 10] Q R
  1. ↑ Van Oven M, Van Geystelen A, Kayser M, Decorte R, Larmuseau HD (2014). "Seeing the wood for the trees: a minimal reference phylogeny for the human Y chromosome". Human Mutation 35 (2): 187–91. doi:10.1002/humu.22468. PMID 24166809.
  2. ↑ International Society of Genetic Genealogy (ISOGG; 2015), Y-DNA Haplogroup Tree 2015. (Access date: 1 February 2015.)
  3. ↑ Haplogroup A0-T is also known as A0'1'2'3'4.
  4. ↑ Haplogroup A1 is also known as A1'2'3'4.
  5. ↑ Haplogroup LT (L298/P326) is also known as Haplogroup K1.
  6. ↑ Haplogroup NO (M214) is also known as Haplogroup K2a (although the present Haplogroup K2e was also previously known as "K2a").
  7. ↑ Haplogroup K2b (M1221/P331/PF5911) is also known as Haplogroup MPS.
  8. ↑ Haplogroup K2e (K-M147) was previously known as "Haplogroup X" and "K2a" (but is a sibling subclade of the present K2a, also known as Haplogroup NO).
  9. ↑ Haplogroup K2b1 (P397/P399) is similar to the former Haplogroup MS, but has a broader and more complex internal structure.
  10. ↑ Haplogroup S (S-M230) was previously known as Haplogroup K5.

References

  1. 1 2 3 Underhill 2009.
  2. 1 2 Kivisild 2003.
  3. ↑ Mirabal 2009.
  4. ↑ Sengupta 2005.
  5. ↑ Sahoo 2006.
  6. ↑ Sharma 2009.
  7. ↑ Thangaraj 2010.
  8. ↑ Sharma (2012).
  9. ↑ Regueiro 2006.
  10. 1 2 Semino 2000.
  11. ↑ Zhao 2009.
  12. ↑ (Keyser 2009)
  13. ↑ Kivisild 2003a.
  14. ↑ J. Freder, Die mittelalterlichen Skelette von Usedom [The mediaeval skeletons of Usedom], Berlin 2010, p. 86 (Dissertation Free University Berlin 2010).
  15. ↑ Peter Gwozdw. M458, L260, CTS11962
  16. ↑ Haplogroup R1a (Y-DNA)

Sources

  • Adams, Susan M.; Bosch, Elena; Balaresque, Patricia L.; Ballereau, Stéphane J.; Lee, Andrew C.; Arroyo, Eduardo; López-Parra, Ana M.; Aler, Mercedes; et al. (2008). "The Genetic Legacy of Religious Diversity and Intolerance: Paternal Lineages of Christians, Jews, and Muslims in the Iberian Peninsula". American Journal of Human Genetics 83 (6): 725–36. doi:10.1016/j.ajhg.2008.11.007. PMC: 2668061. PMID 19061982. 
  • Al Zahery, N.; Semino, O.; Benuzzi, G.; Magri, C.; Passarino, G.; Torroni, A.; Santachiara-Benerecetti, A.S. (2003). "Y-chromosome and mtDNA polymorphisms in Iraq, a crossroad of the early human dispersal and of post-Neolithic migrations". Molecular Phylogenetics and Evolution 28 (3): 458–72. doi:10.1016/S1055-7903(03)00039-3. PMID 12927131. 
  • Balanovsky, Oleg; Rootsi, Siiri; Pshenichnov, Andrey; Kivisild, Toomas; Churnosov, Michail; Evseeva, Irina; Pocheshkhova, Elvira; Boldyreva, Margarita; et al. (2008). "Two Sources of the Russian Patrilineal Heritage in Their Eurasian Context". American Journal of Human Genetics 82 (1): 236–50. doi:10.1016/j.ajhg.2007.09.019. PMC: 2253976. PMID 18179905. 
  • Bamshad, M.; Kivisild, T; Watkins, WS; Dixon, ME; Ricker, CE; Rao, BB; Naidu, JM; Prasad, BV; et al. (2001). "Genetic Evidence on the Origins of Indian Caste Populations". Genome Research 11 (6): 994–1004. doi:10.1101/gr.GR-1733RR. PMC: 311057. PMID 11381027. 
  • Barać, Lovorka; Peričić, Marijana; Klarić, Irena Martinović; Rootsi, Siiri; Janićijević, Branka; Kivisild, Toomas; Parik, Jüri; Rudan, Igor; et al. (2003). "Y chromosomal heritage of Croatian population and its island isolates". European Journal of Human Genetics 11 (7): 535–42. doi:10.1038/sj.ejhg.5200992. PMID 12825075. 
  • Battaglia, Vincenza; Fornarino, Simona; Al-Zahery, Nadia; Olivieri, Anna; Pala, Maria; Myres, Natalie M; King, Roy J; Rootsi, Siiri; et al. (2008). "Y-chromosomal evidence of the cultural diffusion of agriculture in southeast Europe". European Journal of Human Genetics 17 (6): 820–30. doi:10.1038/ejhg.2008.249. PMC: 2947100. PMID 19107149. 
  • Behar, Doron M.; Thomas, Mark G.; Skorecki, Karl; Hammer, Michael F.; Bulygina, Ekaterina; Rosengarten, Dror; Jones, Abigail L.; Held, Karen; et al. (2003). "Multiple Origins of Ashkenazi Levites: Y Chromosome Evidence for Both Near Eastern and European Ancestries". American Journal of Human Genetics 73 (4): 768–79. doi:10.1086/378506. PMC: 1180600. PMID 13680527. 
  • Bouakaze, C.; Keyser, C.; Amory, S.; Crubézy, E.; Ludes, B. (2007). "First successful assay of Y-SNP typing by SNaPshot minisequencing on ancient DNA". International Journal of Legal Medicine 121 (6): 493–9. doi:10.1007/s00414-007-0177-3. PMID 17534642. 
  • Bowden, G. R.; Balaresque, P.; King, T. E.; Hansen, Z.; Lee, A. C.; Pergl-Wilson, G.; Hurley, E.; Roberts, S. J.; et al. (2008). "Excavating Past Population Structures by Surname-Based Sampling: The Genetic Legacy of the Vikings in Northwest England". Molecular Biology and Evolution 25 (2): 301–9. doi:10.1093/molbev/msm255. PMC: 2628767. PMID 18032405. 
  • Bray, S. M.; Mulle, J. G.; Dodd, A. F.; Pulver, A. E.; Wooding, S.; Warren, S. T. (2010). "Signatures of founder effects, admixture, and selection in the Ashkenazi Jewish population". Proceedings of the National Academy of Sciences 107 (37): 16222–7. Bibcode:2010PNAS..10716222B. doi:10.1073/pnas.1004381107. PMC: 2941333. PMID 20798349. 
  • Capelli, Cristian; Redhead, Nicola; Abernethy, Julia K.; Gratrix, Fiona; Wilson, James F.; Moen, Torolf; Hervig, Tor; Richards, Martin; et al. (2003). "A Y Chromosome Census of the British Isles". Current Biology 13 (11): 979–84. doi:10.1016/S0960-9822(03)00373-7. PMID 12781138. 
  • Cinnioğlu, Cengiz; King, Roy; Kivisild, Toomas; Kalfoglu, Ersi; Atasoy, Sevil; Cavalleri, Gianpiero L.; Lillie, Anita S.; Roseman, Charles C.; et al. (2004). "Excavating Y-chromosome haplotype strata in Anatolia". Human Genetics 114 (2): 127–48. doi:10.1007/s00439-003-1031-4. PMID 14586639. 
  • Consortium, T. Y C. (2001). "A Nomenclature System for the Tree of Human Y-Chromosomal Binary Haplogroups". Genome Research 12 (2): 339–48. doi:10.1101/gr.217602. PMC: 155271. PMID 11827954. 
  • Cordaux, Richard; Aunger, Robert; Bentley, Gillian; Nasidze, Ivane; Sirajuddin, S.M.; Stoneking, Mark (2004). "Independent Origins of Indian Caste and Tribal Paternal Lineages". Current Biology 14 (3): 231–5. doi:10.1016/j.cub.2004.01.024. PMID 14761656. 
  • Dupuy, Berit Myhre; Stenersen, Margurethe; Lu, Tim T.; Olaisen, Bjørnar (2005). "Geographical heterogeneity of Y-chromosomal lineages in Norway". Forensic Science International 164 (1): 10–9. doi:10.1016/j.forsciint.2005.11.009. PMID 16337760. 
  • Firasat, Sadaf; Khaliq, Shagufta; Mohyuddin, Aisha; Papaioannou, Myrto; Tyler-Smith, Chris; Underhill, Peter A; Ayub, Qasim (2006). "Y-chromosomal evidence for a limited Greek contribution to the Pathan population of Pakistan". European Journal of Human Genetics 15 (1): 121–6. doi:10.1038/sj.ejhg.5201726. PMC: 2588664. PMID 17047675. 
  • Flores, Carlos; Maca-Meyer, Nicole; Larruga, Jose M.; Cabrera, Vicente M.; Karadsheh, Naif; Gonzalez, Ana M. (2005). "Isolates in a corridor of migrations: A high-resolution analysis of Y-chromosome variation in Jordan". Journal of Human Genetics 50 (9): 435–41. doi:10.1007/s10038-005-0274-4. PMID 16142507. 
  • Fornarino, Simona; Pala, Maria; Battaglia, Vincenza; Maranta, Ramona; Achilli, Alessandro; Modiano, Guido; Torroni, Antonio; Semino, Ornella; Santachiara-Benerecetti, Silvana A (2009). "Mitochondrial and Y-chromosome diversity of the Tharus (Nepal): A reservoir of genetic variation". BMC Evolutionary Biology 9: 154. doi:10.1186/1471-2148-9-154. PMC: 2720951. PMID 19573232. 
  • Gwozdz (2009). "Y-STR Mountains in Haplospace, Part II: Application to Common Polish Clades" (PDF). Journal of Genetic Genealogy 5 (2). 
  • Haak, W.; Brandt, G.; Jong, H. N. d.; Meyer, C.; Ganslmeier, R.; Heyd, V.; Hawkesworth, C.; Pike, A. W. G.; et al. (2008). "Ancient DNA, Strontium isotopes, and osteological analyses shed light on social and kinship organization of the Later Stone Age". Proceedings of the National Academy of Sciences 105 (47): 18226–31. Bibcode:2008PNAS..10518226H. doi:10.1073/pnas.0807592105. PMC: 2587582. PMID 19015520. 
  • Haber, Marc; Platt, Daniel E.; Ashrafian Bonab, Maziar; Youhanna, Sonia C.; Soria-Hernanz, David F.; Martínez-Cruz, Begoña; Douaihy, Bouchra; Ghassibe-Sabbagh, Michella; et al. (2012). Kayser, Manfred, ed. "Afghanistan's Ethnic Groups Share a Y-Chromosomal Heritage Structured by Historical Events". PLoS ONE 7 (3): e34288. Bibcode:2012PLoSO...734288H. doi:10.1371/journal.pone.0034288. PMC: 3314501. PMID 22470552. 
  • Hammer, Michael F.; Behar, Doron M.; Karafet, Tatiana M.; Mendez, Fernando L.; Hallmark, Brian; Erez, Tamar; Zhivotovsky, Lev A.; Rosset, Saharon; Skorecki, Karl (2009). "Response". Human Genetics 126 (5): 725–726. doi:10.1007/s00439-009-0747-1. 
  • Helgason, Agnar; Sigurðardóttir, Sigrún; Nicholson, Jayne; Sykes, Bryan; Hill, Emmeline W.; Bradley, Daniel G.; Bosnes, Vidar; Gulcher, Jeffery R.; et al. (2000). "Estimating Scandinavian and Gaelic Ancestry in the Male Settlers of Iceland". American Journal of Human Genetics 67 (3): 697–717. doi:10.1086/303046. PMC: 1287529. PMID 10931763. 
  • Karafet, T. M.; Mendez, F. L.; Meilerman, M. B.; Underhill, P. A.; Zegura, S. L.; Hammer, M. F. (2008). "New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree". Genome Research 18 (5): 830–8. doi:10.1101/gr.7172008. PMC: 2336805. PMID 18385274. 
  • Kasperaviciūte, D.; Kučinskas, V.; Stoneking, M. (2005). "Y Chromosome and Mitochondrial DNA Variation in Lithuanians". Annals of Human Genetics 68 (5): 438–52. doi:10.1046/j.1529-8817.2003.00119.x. PMID 15469421. 
  • Kayser, Manfred; Lao, Oscar; Anslinger, Katja; Augustin, Christa; Bargel, Grazyna; Edelmann, Jeanett; Elias, Sahar; Heinrich, Marielle; et al. (2005). "Significant genetic differentiation between Poland and Germany follows present-day political borders, as revealed by Y-chromosome analysis". Human Genetics 117 (5): 428–43. doi:10.1007/s00439-005-1333-9. PMID 15959808. 
  • Keyser, Christine; Bouakaze, Caroline; Crubézy, Eric; Nikolaev, Valery G.; Montagnon, Daniel; Reis, Tatiana; Ludes, Bertrand (2009). "Ancient DNA provides new insights into the history of south Siberian Kurgan people". Human Genetics 126 (3): 395–410. doi:10.1007/s00439-009-0683-0. PMID 19449030. 
  • Kharkov, V. N.; Stepanov, V. A.; Borinskaya, S. A.; Kozhekbaeva, Zh. M.; Gusar, V. A.; Grechanina, E. Ya.; Puzyrev, V. P.; Khusnutdinova, E. K.; Yankovsky, N. K. (2004). "Gene Pool Structure of Eastern Ukrainians as Inferred from the Y-Chromosome Haplogroups". Russian Journal of Genetics 40 (3): 326–331. doi:10.1023/B:RUGE.0000021635.80528.2f. 
  • Kharkov, V. N.; Stepanov, V. A.; Feshchenko, S. P.; Borinskaya, S. A.; Yankovsky, N. K.; Puzyrev, V. P. (2005). "Frequencies of Y Chromosome Binary Haplogroups in Belarusians". Russian Journal of Genetics 41 (8): 928–931. doi:10.1007/s11177-005-0182-x. 
  • Kharkov, V. N.; Stepanov, V. A.; Medvedeva, O. F.; Spiridonova, M. G.; Voevoda, M. I.; Tadinova, V. N.; Puzyrev, V. P. (2007). "Gene Pool Differences between Northern and Southern Altaians Inferred from the Data on Y-Chromosomal Haplogroups" (PDF). Russian journal of Genetics 43 (5): 551–562. doi:10.1134/S1022795407050110. 
  • King, R. J.; Özcan, S. S.; Carter, T.; Kalfoğlu, E.; Atasoy, S.; Triantaphyllidis, C.; Kouvatsi, A.; Lin, A. A.; et al. (2008). "Differential Y-chromosome Anatolian Influences on the Greek and Cretan Neolithic". Annals of Human Genetics 72 (2): 205–14. doi:10.1111/j.1469-1809.2007.00414.x. PMID 18269686. 
  • Kivisild, T.; Rootsi, S.; Metspalu, M.; Mastana, S.; Kaldma, K.; Parik, J.; Metspalu, E.; Adojaan, M.; et al. (2003). "The Genetic Heritage of the Earliest Settlers Persists Both in Indian Tribal and Caste Populations". American Journal of Human Genetics 72 (2): 313–32. doi:10.1086/346068. PMC: 379225. PMID 12536373. 
  • Kivisild, Toomas; et al. (2003a). "The Genetics of Language and Farming Spread in India". In Bellwood P, Renfrew C. Examining the farming/language dispersal hypothesis (PDF). McDonald Institute for Archaeological Research, Cambridge, United Kingdom. pp. 215–222. 
  • Lalueza-Fox, C.; Sampietro, M. L.; Gilbert, M. T. P.; Castri, L.; Facchini, F.; Pettener, D.; Bertranpetit, J. (2004). "Unravelling migrations in the steppe: Mitochondrial DNA sequences from ancient Central Asians". Proceedings of the Royal Society B 271 (1542): 941–7. doi:10.1098/rspb.2004.2698. PMC: 1691686. PMID 15255049. 
  • Lell, Jeffrey T.; Sukernik, Rem I.; Starikovskaya, Yelena B.; Su, Bing; Jin, Li; Schurr, Theodore G.; Underhill, Peter A.; Wallace, Douglas C. (2002). "The Dual Origin and Siberian Affinities of Native American Y Chromosomes". American Journal of Human Genetics 70 (1): 192–206. doi:10.1086/338457. PMC: 384887. PMID 11731934. 
  • Luca, F.; Di Giacomo, F.; Benincasa, T.; Popa, L.O.; Banyko, J.; Kracmarova, A.; Malaspina, P.; Novelletto, A.; Brdicka, R. (2006). "Y-chromosomal variation in the Czech Republic". American Journal of Physical Anthropology 132 (1): 132–9. doi:10.1002/ajpa.20500. PMID 17078035. 
  • Marjanovic, D.; Fornarino, S.; Montagna, S.; Primorac, D.; Hadziselimovic, R.; Vidovic, S.; Pojskic, N.; Battaglia, V.; et al. (2005). "The Peopling of Modern Bosnia-Herzegovina: Y-chromosome Haplogroups in the Three Main Ethnic Groups". Annals of Human Genetics 69 (6): 757–63. doi:10.1111/j.1529-8817.2005.00190.x. PMID 16266413. 
  • Mirabal, Sheyla; Regueiro, Maria; Cadenas, Alicia M; Cavalli-Sforza, L Luca; Underhill, Peter A; Verbenko, Dmitry A; Limborska, Svetlana A; Herrera, Rene J (2009). "Y-Chromosome distribution within the geo-linguistic landscape of northwestern Russia". European Journal of Human Genetics 17 (10): 1260–73. doi:10.1038/ejhg.2009.6. PMC: 2986641. PMID 19259129. 
  • Mohammad, T; Xue, Y; Evison, M; Tyler-Smith, C (2009). "Genetic structure of nomadic Bedouin from Kuwait". Heredity 103 (5): 425–33. doi:10.1038/hdy.2009.72. PMC: 2869035. PMID 19639002. 
  • Mukherjee, Namita; Nebel, Almut; Oppenheim, Ariella; Majumder, Partha P. (2001). "High-resolution analysis of Y-chromosomal polymorphisms reveals signatures of population movements from central Asia and West Asia into India". Journal of Genetics 80 (3): 125–35. doi:10.1007/BF02717908. PMID 11988631. 
  • Nasidze, I.; Ling, E. Y. S.; Quinque, D.; Dupanloup, I.; Cordaux, R.; Rychkov, S.; Naumova, O.; Zhukova, O.; et al. (2004). "Mitochondrial DNA and Y-Chromosome Variation in the Caucasus". Annals of Human Genetics 68 (3): 205–21. doi:10.1046/j.1529-8817.2004.00092.x. PMID 15180701. 
  • Nasidze, Ivan; Quinque, Dominique; Ozturk, Murat; Bendukidze, Nina; Stoneking, Mark (2005). "MtDNA and Y-chromosome Variation in Kurdish Groups". Annals of Human Genetics 69 (4): 401–12. doi:10.1046/j.1529-8817.2005.00174.x. PMID 15996169. 
  • Nebel, A; Filon, D; Brinkmann, B; Majumder, P; Faerman, M; Oppenheim, A (2001). "The Y Chromosome Pool of Jews as Part of the Genetic Landscape of the Middle East". American Journal of Human Genetics 69 (5): 1095–112. doi:10.1086/324070. PMC: 1274378. PMID 11573163. 
  • Passarino, Giuseppe; Semino, Ornella; Magri, Chiara; Al-Zahery, Nadia; Benuzzi, Giorgia; Quintana-Murci, Lluis; Andellnovic, Slmun; Bullc-Jakus, Floriana; et al. (2001). "The 49a,f haplotype 11 is a new marker of the EU19 lineage that traces migrations from northern regions of the black sea". Human Immunology 62 (9): 922–32. doi:10.1016/S0198-8859(01)00291-9. PMID 11543894. 
  • Passarino, Giuseppe; Cavalleri, Gianpiero L; Lin, Alice A; Cavalli-Sforza, Luigi Luca; Børresen-Dale, Anne-Lise; Underhill, Peter A (2002). "Different genetic components in the Norwegian population revealed by the analysis of mtDNA and Y chromosome polymorphisms". European Journal of Human Genetics 10 (9): 521–9. doi:10.1038/sj.ejhg.5200834. PMID 12173029. 
  • Pawlowski, R; Dettlaff-Kakol, A; MacIejewska, A; Paszkowska, R; Reichert, M; Jezierski, G (2002). "Population genetics of 9 Y-chromosome STR loci w Northern Poland". Archiwum medycyny sadowej i kryminologii 52 (4): 261–77. PMID 14669672. 
  • Pericić, M.; Lauc, LB; Klarić, IM; Rootsi, S; Janićijevic, B; Rudan, I; Terzić, R; Colak, I; et al. (2005). "High-Resolution Phylogenetic Analysis of Southeastern Europe Traces Major Episodes of Paternal Gene Flow Among Slavic Populations". Molecular Biology and Evolution 22 (10): 1964–75. doi:10.1093/molbev/msi185. PMID 15944443. 
  • Qamar, Raheel; Ayub, Qasim; Mohyuddin, Aisha; Helgason, Agnar; Mazhar, Kehkashan; Mansoor, Atika; Zerjal, Tatiana; Tyler-Smith, Chris; Mehdi, S. Qasim (2002). "Y-Chromosomal DNA Variation in Pakistan". American Journal of Human Genetics 70 (5): 1107–24. doi:10.1086/339929. PMC: 447589. PMID 11898125. 
  • Quintana-Murci, Lluís; Krausz, Csilla; Zerjal, Tatiana; Sayar, S.Hamid; Hammer, Michael F.; Mehdi, S.Qasim; Ayub, Qasim; Qamar, Raheel; et al. (2001). "Y-Chromosome Lineages Trace Diffusion of People and Languages in Southwestern Asia". American Journal of Human Genetics 68 (2): 537–42. doi:10.1086/318200. PMC: 1235289. PMID 11133362. 
  • Rebala, Krzysztof; Mikulich, Alexei I.; Tsybovsky, Iosif S.; Siváková, Daniela; Džupinková, Zuzana; Szczerkowska-Dobosz, Aneta; Szczerkowska, Zofia (2007). "Y-STR variation among Slavs: Evidence for the Slavic homeland in the middle Dnieper basin". Journal of Human Genetics 52 (5): 406–14. doi:10.1007/s10038-007-0125-6. PMID 17364156. 
  • Regueiro, M.; Cadenas, A.M.; Gayden, T.; Underhill, P.A.; Herrera, R.J. (2006). "Iran: Tricontinental Nexus for Y-Chromosome Driven Migration". Human Heredity 61 (3): 132–43. doi:10.1159/000093774. PMID 16770078. 
  • Rosser, Z; Zerjal, T; Hurles, M; Adojaan, M; Alavantic, D; Amorim, A; Amos, W; Armenteros, M; et al. (2000). "Y-Chromosomal Diversity in Europe is Clinal and Influenced Primarily by Geography, Rather than by Language". American Journal of Human Genetics 67 (6): 1526–43. doi:10.1086/316890. PMC: 1287948. PMID 11078479. 
  • Saha, Anjana; Sharma, Swarkar; Bhat, Audesh; Pandit, Awadesh; Bamezai, Ramesh (2005). "Genetic affinity among five different population groups in India reflecting a Y-chromosome gene flow". Journal of Human Genetics 50 (1): 49–51. doi:10.1007/s10038-004-0219-3. PMID 15611834. 
  • Sahoo, S.; Singh, A; Himabindu, G; Banerjee, J; Sitalaximi, T; Gaikwad, S; Trivedi, R; Endicott, P; et al. (2006). "A prehistory of Indian Y chromosomes: Evaluating demic diffusion scenarios". Proceedings of the National Academy of Sciences 103 (4): 843–8. Bibcode:2006PNAS..103..843S. doi:10.1073/pnas.0507714103. PMC: 1347984. PMID 16415161. 
  • Sanchez, Juan J; Børsting, Claus; Hallenberg, Charlotte; Buchard, Anders; Hernandez, Alexis; Morling, Niels (2003). "Multiplex PCR and minisequencing of SNPs—a model with 35 Y chromosome SNPs". Forensic Science International 137 (1): 74–84. doi:10.1016/S0379-0738(03)00299-8. PMID 14550618. 
  • Scozzari, Rosaria; Cruciani, Fulvio; Pangrazio, Alessandra; Santolamazza, Piero; Vona, Giuseppe; Moral, Pedro; Latini, Veronica; Varesi, Laurent; et al. (2001). "Human Y-chromosome variation in the Western Mediterranean area: Implications for the peopling of the region". Human Immunology 62 (9): 871–84. doi:10.1016/S0198-8859(01)00286-5. PMID 11543889. 
  • Semino, O.; Passarino, G; Oefner, PJ; Lin, AA; Arbuzova, S; Beckman, LE; De Benedictis, G; Francalacci, P; et al. (2000). "The Genetic Legacy of Paleolithic Homo sapiens sapiens in Extant Europeans: A Y Chromosome Perspective". Science 290 (5494): 1155–9. Bibcode:2000Sci...290.1155S. doi:10.1126/science.290.5494.1155. PMID 11073453. 
  • Sengupta, Sanghamitra; Zhivotovsky, Lev A.; King, Roy; Mehdi, S.Q.; Edmonds, Christopher A.; Chow, Cheryl-Emiliane T.; Lin, Alice A.; Mitra, Mitashree; et al. (2005). "Polarity and Temporality of High-Resolution Y-Chromosome Distributions in India Identify Both Indigenous and Exogenous Expansions and Reveal Minor Genetic Influence of Central Asian Pastoralists". American Journal of Human Genetics 78 (2): 202–21. doi:10.1086/499411. PMC: 1380230. PMID 16400607. 
  • Sharma, Swarkar; Rai, Ekta; Sharma, Prithviraj; Jena, Mamata; Singh, Shweta; Darvishi, Katayoon; Bhat, Audesh K; Bhanwer, A J S; et al. (2009). "The Indian origin of paternal haplogroup R1a1* substantiates the autochthonous origin of Brahmins and the caste system". Journal of Human Genetics 54 (1): 47–55. doi:10.1038/jhg.2008.2. PMID 19158816. 
  • Soares, Pedro; Achilli, Alessandro; Semino, Ornella; Davies, William; MacAulay, Vincent; Bandelt, Hans-Jürgen; Torroni, Antonio; Richards, Martin B. (2010). "The Archaeogenetics of Europe". Current Biology 20 (4): R174–83. doi:10.1016/j.cub.2009.11.054. PMID 20178764. 
  • Tambets, K; Rootsi, S; Kivisild, T; Help, H; Serk, P; Loogväli, EL; Tolk, HV; Reidla, M; et al. (2004). "The Western and Eastern Roots of the Saami—the Story of Genetic 'Outliers' Told by Mitochondrial DNA and Y Chromosomes". American Journal of Human Genetics 74 (4): 661–682. doi:10.1086/383203. PMC: 1181943. PMID 15024688. 
  • Thangaraj, Kumarasamy; Naidu, B. Prathap; Crivellaro, Federica; Tamang, Rakesh; Upadhyay, Shashank; Sharma, Varun Kumar; Reddy, Alla G.; Walimbe, S. R.; et al. (2010). Cordaux, Richard, ed. "The Influence of Natural Barriers in Shaping the Genetic Structure of Maharashtra Populations". PLoS ONE 5 (12): e15283. Bibcode:2010PLoSO...515283T. doi:10.1371/journal.pone.0015283. PMC: 3004917. PMID 21187967. 
  • Thanseem, Ismail; Thangaraj, Kumarasamy; Chaubey, Gyaneshwer; Singh, Vijay; Bhaskar, Lakkakula VKS; Reddy, B Mohan; Reddy, Alla G; Singh, Lalji (2006). "Genetic affinities among the lower castes and tribal groups of India: Inference from Y chromosome and mitochondrial DNA". BMC Genetics 7: 42. doi:10.1186/1471-2156-7-42. PMC: 1569435. PMID 16893451. 
  • Underhill, Peter A; Myres, Natalie M; Rootsi, Siiri; Metspalu, Mait; Zhivotovsky, Lev A; King, Roy J; Lin, Alice A; Chow, Cheryl-Emiliane T; et al. (2009). "Separating the post-Glacial coancestry of European and Asian Y chromosomes within haplogroup R1a". European Journal of Human Genetics 18 (4): 479–84. doi:10.1038/ejhg.2009.194. PMC: 2987245. PMID 19888303. 
  • Underhill PA, et al. (2010). "Separating the post-Glacial coancestry of European and Asian Y chromosomes within haplogroup R1a". European Journal of Human Genetics 18 (4): 479–484. doi:10.1038/ejhg.2009.194. PMC: 2987245. PMID 19888303. 
  • Völgyi, Antónia; Zalán, Andrea; Szvetnik, Enikő; Pamjav, Horolma (2008). "Hungarian population data for 11 Y-STR and 49 Y-SNP markers". Forensic Science International: Genetics 3 (2): e27–8. doi:10.1016/j.fsigen.2008.04.006. PMID 19215861. 
  • Wang, Wei; Wise, Cheryl; Baric, Tom; Black, Michael L.; Bittles, Alan H. (2003). "The origins and genetic structure of three co-resident Chinese Muslim populations: The Salar, Bo'an and Dongxiang". Human Genetics 113 (3): 244–52. doi:10.1007/s00439-003-0948-y. PMID 12759817. 
  • Weale, Michael; Yepiskoposyan, Levon; Jager, Rolf; Hovhannisyan, Nelli; Khudoyan, Armine; Burbage-Hall, Oliver; Bradman, Neil; Thomas, Mark (2001). "Armenian Y chromosome haplotypes reveal strong regional structure within a single ethno-national group". Human Genetics 109 (6): 659–74. doi:10.1007/s00439-001-0627-9. PMID 11810279. 
  • Weale, ME; Weiss, DA; Jager, RF; Bradman, N; Thomas, MG (2002). "Y chromosome evidence for Anglo-Saxon mass migration". Molecular Biology and Evolution 19 (7): 1008–21. doi:10.1093/oxfordjournals.molbev.a004160. PMID 12082121. 
  • Wells, R. S.; Yuldasheva, N; Ruzibakiev, R; Underhill, PA; Evseeva, I; Blue-Smith, J; Jin, L; Su, B; et al. (2001). "The Eurasian Heartland: A continental perspective on Y-chromosome diversity". Proc. Natl. Acad. Sci. U.S.A. 98 (18): 10244–9. Bibcode:2001PNAS...9810244W. doi:10.1073/pnas.171305098. PMC: 56946. PMID 11526236. 
  • Wilson, J. F.; Weiss, D. A.; Richards, M.; Thomas, M. G.; Bradman, N.; Goldstein, D. B. (2001). "Genetic evidence for different male and female roles during cultural transitions in the British Isles". Proceedings of the National Academy of Sciences 98 (9): 5078–83. Bibcode:2001PNAS...98.5078W. doi:10.1073/pnas.071036898. PMC: 33166. PMID 11287634. 
  • Zerjal, T; Beckman, L; Beckman, G; Mikelsaar, AV; Krumina, A; Kucinskas, V; Hurles, ME; Tyler-Smith, C (2001). "Geographical, linguistic, and cultural influences on genetic diversity: Y-chromosomal distribution in Northern European populations". Molecular Biology and Evolution 18 (6): 1077–87. doi:10.1093/oxfordjournals.molbev.a003879. PMID 11371596. 
  • Zerjal, Tatiana; Wells, R. Spencer; Yuldasheva, Nadira; Ruzibakiev, Ruslan; Tyler-Smith, Chris (2002). "A Genetic Landscape Reshaped by Recent Events: Y-Chromosomal Insights into Central Asia". American Journal of Human Genetics 71 (3): 466–82. doi:10.1086/342096. PMC: 419996. PMID 12145751. 
  • Zhao, Zhongming; Khan, Faisal; Borkar, Minal; Herrera, Rene; Agrawal, Suraksha (2009). "Presence of three different paternal lineages among North Indians: A study of 560 Y chromosomes". Annals of Human Biology 36 (1): 46–59. doi:10.1080/03014460802558522. PMC: 2755252. PMID 19058044. 
  • Zhivotovsky, L; Underhill, P; Cinnioglu, C; Kayser, M; Morar, B; Kivisild, T; Scozzari, R; Cruciani, F; et al. (2004). "The Effective Mutation Rate at Y Chromosome Short Tandem Repeats, with Application to Human Population-Divergence Time". American Journal of Human Genetics 74 (1): 50–61. doi:10.1086/380911. PMC: 1181912. PMID 14691732. 
  • Zhou, Ruixia; An, Lizhe; Wang, Xunling; Shao, Wei; Lin, Gonghua; Yu, Weiping; Yi, Lin; Xu, Shijian; et al. (2007). "Testing the hypothesis of an ancient Roman soldier origin of the Liqian people in northwest China: A Y-chromosome perspective". Journal of Human Genetics 52 (7): 584–91. doi:10.1007/s10038-007-0155-0. PMID 17579807. 

Books

  • Gimbutas (1970). Indo-European and Indo-Europeans. Univ. of Pennsylvania Press, Philadelphia, PA. pp. 155–195. 
  • Malaspina (2003). Analysis of Y-chromosome variation in modern populations at the European-Asian border (PDF). pp. 309–313.  in K. Boyle, C. Renfrew, and M. Levine, eds. Ancient interactions: east and west in Eurasia. McDonald Institute for Archaeological Research Monograph Series, Cambridge University Press, Cambridge
  • Wells, Spencer (2002). The Journey of Man: A Genetic Odyssey. Princeton University Press. ISBN 0-691-11532-X. 

Conference posters

Dissertations

Websites

External links

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