SNAPC1
| Small nuclear RNA activating complex, polypeptide 1, 43kDa | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | SNAPC1 ; PTFgamma; SNAP43 | ||||||||||||
| External IDs | OMIM: 600591 MGI: 1922877 HomoloGene: 2317 GeneCards: SNAPC1 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 6617 | 75627 | |||||||||||
| Ensembl | ENSG00000023608 | ENSMUSG00000021113 | |||||||||||
| UniProt | Q16533 | Q8K0S9 | |||||||||||
| RefSeq (mRNA) | NM_003082 | NM_178392 | |||||||||||
| RefSeq (protein) | NP_003073 | NP_848479 | |||||||||||
| Location (UCSC) |
Chr 14: 61.76 – 61.8 Mb |
Chr 12: 73.96 – 73.98 Mb | |||||||||||
| PubMed search | |||||||||||||
snRNA-activating protein complex subunit 1 is a protein that in humans is encoded by the SNAPC1 gene.[1][2]
Interactions
SNAPC1 has been shown to interact with SNAPC4,[3] SNAPC3[3][4] and Retinoblastoma protein.[5]
References
- ↑ Maeng JH, Yoon JB (September 1998). "The human PTFgamma/SNAP43 gene: structure, chromosomal location, and identification of a VNTR in 5'-UTR". J Biochem 124 (1): 23–7. doi:10.1093/oxfordjournals.jbchem.a022085. PMID 9644240.
- ↑ "Entrez Gene: SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa".
- 1 2 Ma, B; Hernandez N (February 2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". J. Biol. Chem. (United States) 276 (7): 5027–35. doi:10.1074/jbc.M009301200. ISSN 0021-9258. PMID 11056176.
- ↑ Henry, R W; Ma B; Sadowski C L; Kobayashi R; Hernandez N (Dec 1996). "Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc". EMBO J. (ENGLAND) 15 (24): 7129–36. ISSN 0261-4189. PMC 452539. PMID 9003788.
- ↑ Hirsch, H A; Gu L; Henry R W (Dec 2000). "The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression". Mol. Cell. Biol. (UNITED STATES) 20 (24): 9182–91. doi:10.1128/MCB.20.24.9182-9191.2000. ISSN 0270-7306. PMC 102176. PMID 11094070.
Further reading
- Henry RW, Sadowski CL, Kobayashi R, Hernandez N (1995). "A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III". Nature 374 (6523): 653–6. doi:10.1038/374653a0. PMID 7715707.
- Yoon JB, Roeder RG (1996). "Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein". Mol. Cell. Biol. Advances in Molecular and Cell Biology 16 (1): 1–9. doi:10.1016/S1569-2558(08)60061-2. ISBN 978-0-7623-0143-0. PMC 230972. PMID 8524284.
- Henry RW, Ma B, Sadowski CL, et al. (1997). "Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc". EMBO J. 15 (24): 7129–36. PMC 452539. PMID 9003788.
- Ma B, Hernandez N (2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". J. Biol. Chem. 276 (7): 5027–35. doi:10.1074/jbc.M009301200. PMID 11056176.
- Hirsch HA, Gu L, Henry RW (2001). "The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression". Mol. Cell. Biol. 20 (24): 9182–91. doi:10.1128/MCB.20.24.9182-9191.2000. PMC 102176. PMID 11094070.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Hinkley CS, Hirsch HA, Gu L, et al. (2003). "The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition". J. Biol. Chem. 278 (20): 18649–57. doi:10.1074/jbc.M204247200. PMID 12621023.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Gu L, Esselman WJ, Henry RW (2005). "Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC". J. Biol. Chem. 280 (30): 27697–704. doi:10.1074/jbc.M503206200. PMID 15955816.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
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