Sodium tetradecyl sulfate

Sodium tetradecyl sulfate
Systematic (IUPAC) name

Sodium 7-ethyl-2-methyl-4-undecanyl sulfate
Clinical data
AHFS/Drugs.com	Consumer Drug Information
Routes of administration	Intravenous injection
Legal status
Legal status	Prescription only medicine
Identifiers
ATC code	C05BB04 (WHO)
PubChem	CID 14492
ChemSpider	8440^N
UNII	Q1SUG5KBD6^N
ChEMBL	CHEMBL1200354^N
Synonyms	7-Ethyl-2-methyl-4-hendecanol sulfate sodium salt
Chemical data
Formula	C₁₄H₂₉NaO₄S
Molar mass	316.43243 g/mol
SMILES CCCCC(CC)CCC(CC(C)C)OS(=O)(=O)[O-].[Na+]
InChI InChI=1S/C14H30O4S.Na/c1-5-7-8-13(6-2)9-10-14(11-12(3)4)18-19(15,16)17;/h12-14H,5-11H2,1-4H3,(H,15,16,17);/q;+1/p-1^N Key:FVEFRICMTUKAML-UHFFFAOYSA-M^N
^NY (what is this?) (verify)

Sodium tetradecyl sulfate (STS) is a commonly used synonym for 7-ethyl-2-methyl-4-undecanyl sulfate sodium salt^[1] which is anionic surfactant that is the active component of the sclerosant drug Sotradecol. It is commonly used in the treatment of varicose and spider veins of the leg, during the procedure of sclerotherapy. Being a detergent, its action is on the lipid molecules in the cells of the vein wall, causing inflammatory destruction of the internal lining of the vein and thrombus formation eventually leading to sclerosis of the vein. It is used in concentrations ranging from 0.1% to 3% for this purpose. In the UK, Ireland, Italy, Australia, New Zealand and South Africa, it is sold under the trade-name Fibro-Vein in concentrations of 0.2%, 0.5%, 1.0%, and 3%.^[2]

References

↑ "SOTRADECOL® (Sodium tetradecyl sulfate)" (PDF). Retrieved 29 August 2014.
↑ Fibro-Vein history and details

Vasoprotectives (C05)

Antihemorrhoidals for topical use

corticosteroids	Hydrocortisone Prednisolone Betamethasone Fluorometholone Fluocortolone Dexamethasone Fluocinolone acetonide Fluocinonide

local anesthetics	Lidocaine Tetracaine Benzocaine Dibucaine Procaine Oxetacaine Pramocaine

other	Tribenoside

Antivaricose therapy

heparins or heparinoids for topical use	Organo-heparinoid Sodium apolate Heparin Pentosan polysulfate

sclerosing agents for local injection	Monoethanolamine oleate Polidocanol Inverted sugar syrup Sodium tetradecyl sulfate Phenol

other	Calcium dobesilate

Capillary stabilising agents

bioflavonoids	Rutoside Monoxerutin Diosmin Troxerutin Hidrosmin

other	Tribenoside Etamsylate

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