Thymidine monophosphate

Thymidine monophosphate

Names
IUPAC name Thymidine monophosphate
Identifiers
Abbreviations	dTMP
Beilstein Reference	3916216
ChEBI	CHEBI:26999
ChEMBL	ChEMBL394429
ChemSpider	10239189
Jmol 3D model	Interactive image
PubChem	16755631
InChI InChI=1S/C10H15N2O8P/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18)/p-2 Key: GYOZYWVXFNDGLU-UHFFFAOYSA-L
SMILES Cc1cn(C2CC(O)C(COP([O-])([O-])=O)O2)c(:o)[nH]c1:o
Properties
Chemical formula	C10H14N2O8P^1−
Molar mass	321.2005 g mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Thymidine monophosphate (TMP), also known as thymidylic acid (conjugate base thymidylate), deoxythymidine monophosphate (dTMP), or deoxythymidylic acid (conjugate base deoxythymidylate), is a nucleotide that is used as a monomer in DNA. It is an ester of phosphoric acid with the nucleoside thymidine. dTMP consists of a phosphate group, the pentose sugar deoxyribose, and the nucleobase thymine. Unlike the other deoxyribonucleotides, thymidine monophosphate often does not contain the "deoxy" prefix in its name; nevertheless, its symbol often includes a "d" ("dTMP").^[1] Dorland’s Illustrated Medical Dictionary^[2] provides an explanation of the nomenclature variation at its entry for thymidine.

As a substituent, it is called by the prefix thymidylyl-.

See also

• Nucleoside
• Nucleotide
• DNA
• RNA
• Oligonucleotide

References

1. Coghill, Anne M.; Garson, Lorrin R., ed. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.
2. Elsevier, Dorland's Illustrated Medical Dictionary, Elsevier.

External links