Tiemonium iodide

Tiemonium iodide
Systematic (IUPAC) name

4-[3-hydroxy-3-phenyl-3-(2-thienyl)propyl]-4-methylmorpholin-4-ium iodide
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	144-12-7
ATC code	A03AB17 (WHO)
PubChem	CID 72142
ChemSpider	65116
UNII	FZ2LZ7U304^Y
KEGG	D01201
Chemical data
Formula	C₁₈H₂₄INO₂S
Molar mass	445.36 g/mol
SMILES C[N+]1(CCOCC1)CCC(C2=CC=CC=C2)(C3=CC=CS3)O.[I-]
InChI InChI=1S/C18H24NO2S.HI/c1-19(11-13-21-14-12-19)10-9-18(20,17-8-5-15-22-17)16-6-3-2-4-7-16;/h2-8,15,20H,9-14H2,1H3;1H/q+1;/p-1 Key:IOFXEUZPIIUQAG-UHFFFAOYSA-M

Tiemonium iodide is an antimuscarinic. It is poorly absorbed from the gut. The active moiety is tiemonium, a quaternary ammonium cation.^[1]

References

↑ Scoular, I. T.; Monks, Anne; Burgess, C.; Turner, P. (1977). "Human studies on the bioavailability of a quaternary ammonium compound, tiemonium iodide and tiemonium methosulphate". Current Medical Research and Opinion 4 (10): 732–8. doi:10.1185/03007997609112009. PMID 1052164.

Drugs for functional gastrointestinal disorders (A03)

Drugs for
functional
bowel disorders

Antimuscarinics

Tertiary amino group	Oxyphencyclimine Camylofin Mebeverine Trimebutine Rociverine Dicycloverine Dihexyverine Difemerine Piperidolate

Quaternary ammonium compounds	Benzilone Mepenzolate Pipenzolate Glycopyrronium Oxyphenonium Penthienate Methantheline Propantheline Otilonium Tridihexethyl Isopropamide Hexocyclium Poldine Bevonium Diphemanil Tiemonium Prifinium Timepidium Fenpiverinium

Phosphodiesterase
inhibitors

Acting on
serotonin receptors

Other

Belladonna
and derivatives
(antimuscarinics)

tertiary amines: Atropine
Hyoscyamine

Propulsives

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