(3S,6E)-nerolidol synthase

(3S,6E)-nerolidol synthase
Identifiers
EC number 4.2.3.48
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(3S,6E)-nerolidol synthase (EC 4.2.3.48, (E)-nerolidol synthase, nerolidol synthase, (3S)-(E)-nerolidol synthase, FaNES1) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((3S,6E)-nerolidol-forming) .[1][2][3][4] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O \rightleftharpoons (3S,6E)-nerolidol + diphosphate

The enzyme catalyses a step in the formation of (3E)-4,8-dimethylnona-1,3,7-triene.

References

  1. Aharoni, A., Giri, A.P., Verstappen, F.W., Bertea, C.M., Sevenier, R., Sun, Z., Jongsma, M.A., Schwab, W. and Bouwmeester, H.J. (2004). "Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species". Plant Cell 16: 3110–3131. doi:10.1105/tpc.104.023895. PMID 15522848.
  2. Bouwmeester, H.J., Verstappen, F.W., Posthumus, M.A. and Dicke, M. (1999). "Spider mite-induced (3S)-(E)-nerolidol synthase activity in cucumber and lima bean. The first dedicated step in acyclic C11-homoterpene biosynthesis". Plant Physiol. 121: 173–180. doi:10.1104/pp.121.1.173. PMID 10482672.
  3. Degenhardt, J. and Gershenzon, J. (2000). "Demonstration and characterization of (E)-nerolidol synthase from maize: a herbivore-inducible terpene synthase participating in (3E)-4,8-dimethyl-1,3,7-nonatriene biosynthesis". Planta 210: 815–822. doi:10.1007/s004250050684. PMID 10805454.
  4. Arimura, G., Garms, S., Maffei, M., Bossi, S., Schulze, B., Leitner, M., Mithofer, A. and Boland, W. (2008). "Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling". Planta 227: 453–464. doi:10.1007/s00425-007-0631-y. PMID 17924138.

External links

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