4-MeO-DMT

4-MeO-DMT

Systematic (IUPAC) name
2-(4-Methoxy-1H-indol-3-yl)-N,N-dimethylethanamine
Identifiers
CAS Number	3965-97-7
PubChem	CID 12017578
ChemSpider	23126449
ChEMBL	CHEMBL32029
Chemical data
Formula	C13H18N2O
Molar mass	218.30 g·mol^−1
SMILES CN(C)CCC1=CNC2=CC=CC(OC)=C21
InChI InChI=1S/C13H18N2O/c1-15(2)8-7-10-9-14-11-5-4-6-12(16-3)13(10)11/h4-6,9,14H,7-8H2,1-3H3 Key:HFYHBTWTJDAYGW-UHFFFAOYSA-N
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4-MeO-DMT (4-methoxy-N,N-dimethyltryptamine) is a tryptamine derivative which has some central activity in animal tests similar to that of related psychedelic tryptamine drugs, although with significantly lower potency than either 5-MeO-DMT or 4-hydroxy-DMT (psilocin).^[1][2][3][4]

See also

• 4-Acetoxy-DMT
• Alexander Shulgin
• 4-MeO-MiPT

References

1. Glennon RA, Young R, Benington F, Morin RD (February 1982). "Hallucinogens as discriminative stimuli: a comparison of 4-OMe DMT and 5-OMe DMT with their methythio counterparts". Life Sciences 30 (5): 465–7. doi:10.1016/0024-3205(82)90463-5. PMID 6801410.
2. Kline TB, Benington F, Morin RD, Beaton JM (August 1982). "Structure-activity relationships in potentially hallucinogenic N,N-dialkyltryptamines substituted in the benzene moiety". Journal of Medicinal Chemistry 25 (8): 908–13. doi:10.1021/jm00350a005. PMID 7120280.
3. Kline TB, Benington F, Morin RD, Beaton JM, Glennon RA, Domelsmith LN, Houk KN, Rozeboom MD (November 1982). "Structure-activity relationships for hallucinogenic N,N-dialkyltryptamines: photoelectron spectra and serotonin receptor affinities of methylthio and methylenedioxy derivatives". Journal of Medicinal Chemistry 25 (11): 1381–3. doi:10.1021/jm00353a021. PMID 6815326.
4. Nichols DE, Glennon RA. Medicinal Chemistry and Structure-Activity Relationships of Hallucinogens, in Hallucinogens, Neurochemical, Behavioral, and Clinical Perspectives (Raven Press 1984), pp 95-142. ISBN 978-0-89004-990-7