Butaclamol
 | |
| Systematic (IUPAC) name | |
|---|---|
|
(3S,4aS,13bS)-3-(2-Methyl-2-propanyl)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinolin-3-ol | |
| Identifiers | |
| CAS Number | 36504-93-5 |
| ATC code | None |
| PubChem | CID 37459 |
| IUPHAR/BPS | 62 |
| ChemSpider | 34364 |
| UNII |
A7A2802VNL  |
| ChEBI |
CHEBI:73298 |
| ChEMBL |
CHEMBL479587 |
| Chemical data | |
| Formula | C25H31NO |
| Molar mass | 361.52 g/mol |
| |
Butaclamol (AY-23,028) is an antipsychotic which was never marketed.[1] Sold as the hydrochloride salt for use in research, the compound acts as a dopamine receptor antagonist.[2]
Chemistry
pKa = 7.15 (uncorrected for ionic strength)[3]
See also
References
- ↑ Buckingham, J. Dictionary of organic compounds - Google Books. ISBN 9780412540905.
- ↑ http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5=SEARCH_CONCAT_PNO%7CBRAND_KEY&N4=D033%7CSIGMA&N25=0&QS=ON&F=SPEC
- ↑ F. A. Chrzanowski, B. A. McGrogan, B. E. Maryanoff (1985). "The pKa of butaclamol and the mode of butaclamol binding to central dopamine receptors." J. Med. Chem. 28 399-400.
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