Flucindole

Flucindole

Systematic (IUPAC) name
6,8-difluoro-N,N-dimethyl-2,3,4,9-tetrahydro-1H-carbazol-3-amine
Clinical data
Routes of administration	Oral
Legal status
Legal status	Uncontrolled
Identifiers
CAS Number	40594-09-0
ATC code	none
PubChem	CID 38531
ChemSpider	35315
UNII	5CYU0D0S8M
KEGG	D02658
ChEMBL	CHEMBL1882682
Chemical data
Formula	C14H18N2
Molar mass	250.287 g/mol
SMILES CN(C)C1CCC2=C(C1)C3=CC(=CC(=C3N2)F)F
InChI InChI=1S/C14H16F2N2/c1-18(2)9-3-4-13-10(7-9)11-5-8(15)6-12(16)14(11)17-13/h5-6,9,17H,3-4,7H2,1-2H3 Key:FXNCRITWFOVSEP-UHFFFAOYSA-N
(verify)

Flucindole is an antipsychotic with a tricyclic structure, that was never marketed.^[1] It is the 6,8-difluoro derivative of cyclindole.^[2]

Synthesis

Flucindole synthesis:^[3][4]

See also

• Cyclindole
• 5-Fluoro-AMT
• Iprindole

References

1. Wood PL, McQuade PS (1984). "Ciclindole and flucindole: novel tetrahydrocarbazolamine neuroleptics". Progress in Neuro-psychopharmacology & Biological Psychiatry 8 (4-6): 773–7. doi:10.1016/0278-5846(84)90057-5. PMID 6152347.
2. Edelson J, Benziger DP (1980). "Disposition of a series of tetrahydrocarbazoles". Drug Metabolism Reviews 11 (2): 263–89. doi:10.3109/03602538008994027. PMID 7011760.
3. Mooradian, Aram; Dupont, Paul E.; Hlavac, Allan G.; Aceto, Mario D.; Pearl, Jack (1977). "3-Aminotetrahydrocarbazoles as a new series of central nervous system agents". Journal of Medicinal Chemistry 20 (4): 487–492. doi:10.1021/jm00214a005.
4. Aram Mooradian DE 2240211  (1973 to Sterling Drug).