Morazone
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| Systematic (IUPAC) name | |
|---|---|
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1,5-dimethyl-4-[(3-methyl-2-phenylmorpholin-4-yl)methyl]-2-phenyl-1,2-dihydro-3H-pyrazol-3-one | |
| Clinical data | |
| Routes of administration | Oral, SC, IM[1] |
| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number |
6536-18-1  |
| ATC code | none |
| PubChem | CID 39609 |
| ChemSpider |
36216  |
| UNII |
870Q5BL2FN |
| Chemical data | |
| Formula | C23H27N3O2 |
| Molar mass | 377.48 g/mol |
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| (what is this?) (verify) | |
Morazone (Novartrina, Orsimon, Rosimon-Neu, Tarcuzate) is a non-steroidal anti-inflammatory drug (NSAID), originally developed by the German pharmaceutical company Ravensberg in the 1950s, which is used as an analgesic.[1][2][3] It produces phenmetrazine as a major metabolite and has been reported to have been abused as a recreational drug in the past.[4][5][6][7]
See also
References
- 1 2 Seyffart, G. (1991). Drug dosage in Renal Insufficiency. Boston: Kluwer Academic Publishers. p. 399. ISBN 0-7923-0964-2.
- ↑ US patent 2943022, Siemer, H. & Doppstadt, A., "Substituted 1-phenyl-2,3-dimethyl-4-morpholino methyl pyrazolone-(5) Compounds and Process of Making Same", issued 1960-06-28, assigned to Ravensberg
- ↑ J. Buckingham, ed. (1996). Dictionary of Organic Compounds 7. London: Chapman & Hall. p. 4659. ISBN 0-412-54090-8.
- ↑ Bohn, G.; Rücker, G.; Kröger, H. (1976). "Investigations of the decomposition and detection of morazone by thin-layer- and gas-liquid-chromatography". Archives of Toxicology 35 (3): 213–220. PMID 989292.
- ↑ Neugebauer, M. (1984). "Some new urinary metabolites of famprofazone and morazone in man". Journal of Pharmaceutical and Biomedical Analysis 2 (1): 53–60. doi:10.1016/0731-7085(84)80089-8. PMID 16867765.
- ↑ Kingreen, J. C.; Breger, G. (1984). "Pellagra in morazone abuse". Zeitschrift für Hautkrankheiten 59 (9): 573–577. PMID 6145264.
- ↑ Daunderer, M.; Janzen, W. (1972). "Rosimon-NEU--a non-prescription analgesic on the adolescent drug scene". Beiträge zur Gerichtlichen Medizin 29: 138–143. PMID 5081964.
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