Aloxiprin

Aloxiprin

Systematic (IUPAC) name
aluminum 2-acetyloxybenzoate hydroxide
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	9014-67-9
ATC code	B01AC15 (WHO) N02BA02 (WHO)
PubChem	CID 3032790
ChemSpider	2297682
UNII	6QT214X4XU
KEGG	D07421
Chemical data
Formula	C18H15O9
Molar mass	402.288 g/mol
SMILES [Al+3].O=C(Oc1ccccc1C([O-])=O)C.[OH-].[O-]C(=O)c1ccccc1OC(=O)C
InChI InChI=1S/2C9H8O4.Al.H2O/c2*1-6(10)13-8-5-3-2-4-7(8)9(11)12;;/h2*2-5H,1H3,(H,11,12);;1H2/q;;+3;/p-3 Key:MANKSFVECICGLK-UHFFFAOYSA-K
(verify)

Aloxiprin (or aluminium acetylsalicylate) is a medical drug used for the treatment of pain and inflammation associated with muscular skeletal and joint disorders.^[1] It is used for its properties as an anti-inflammatory, antipyretic and analgesic drug.^[1] It is a chemical compound of aluminium hydroxide and aspirin.^[2][3]

Alternative names and combinations

• Palaprin Forte.^[4]
• Askit- A powder combination of aspirin, aloxiprin and caffeine.^[5]

Contraindications

• People with allergies to salicylates.
• People with gastrointestinal ulcers.
• People with liver or kidney damage.
• Pregnant women in the 3rd trimester.
• Women who are breastfeeding.
• Use with other salicylates.
• Use with NSAIDs.

References

1. MIMS. "Aloxiprin". MIMS. Retrieved 16 April 2011.
2. Encarta. "Aloxiprin". Encarta. Retrieved 16 April 2011.
3. CUMMINGS AJ, MARTIN BK, WIGGINS LF (1963). "In vitro and in vivo properties of aloxiprin: a new aluminium derivative of acetylsalicylic acid". J. Pharm. Pharmacol. 15: 56–62. PMID 14024235.
4. Geller J (1968). "A comparative trial of aloxiprin ('Palaprin Forte') and phenylbutazone ('Butazolidin')". The British journal of clinical practice 22 (9): 392–4. PMID 4876729.
5. Net Doctor UK. "Askit Powders". Treatments for joint, muscle and bone conditions. Retrieved 16 April 2011.

External links

• CTD's Aloxiprin page from the Comparative Toxicogenomics Database