Feprazone

Feprazone
Systematic (IUPAC) name

4-(3-methylbut-2-enyl)-1,2-di(phenyl)pyrazolidine-3,5-dione
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
ATC code	M02AA16 (WHO)
PubChem	CID 35455
ChemSpider	32612^Y
UNII	7BVX6J0CGR^Y
KEGG	D01305^Y
Chemical data
Formula	C₂₀H₂₀N₂O₂
Molar mass	320.385 g/mol
SMILES O=C2N(c1ccccc1)N(C(=O)C2C\C=C(/C)C)c3ccccc3
InChI InChI=1S/C20H20N2O2/c1-15(2)13-14-18-19(23)21(16-9-5-3-6-10-16)22(20(18)24)17-11-7-4-8-12-17/h3-13,18H,14H2,1-2H3^Y Key:RBBWCVQDXDFISW-UHFFFAOYSA-N^Y
(verify)

Feprazone (or prenazone) is a drug used for joint and muscular pain.^[1]

It is an analog of butazone but instead of a n-butyl group it is prenylated.

References

↑ Koyama, T.; Izawa, Y.; Wada, H.; Makita, T.; Hashimoto, Y.; Enomoto, M. (1982). "Toxicological aspects of feprazone, a new nonsteroidal anti-inflammatory drug". Toxicology and applied pharmacology 64 (2): 255–270. doi:10.1016/0041-008X(82)90222-8. PMID 7123554.

Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)

Pyrazolones / Pyrazolidines	Aminophenazone Ampyrone Azapropazone Clofezone Famprofazone Feprazone Kebuzone Metamizole Mofebutazone Morazone Nifenazone Oxyphenbutazone Phenazone Phenylbutazone Propyphenazone Sulfinpyrazone Suxibuzone^‡

Salicylates	Aspirin (acetylsalicylic acid)^# Aloxiprin Benorylate Carbasalate calcium Diflunisal Dipyrocetyl Ethenzamide Guacetisal Magnesium salicylate Methyl salicylate Salsalate Salicin Salicylamide Salicylic acid (salicylate) Sodium salicylate

Acetic acid derivatives and related substances	Aceclofenac Acemetacin Alclofenac Amfenac Bendazac Bromfenac Bumadizone Bufexamac Diclofenac Difenpiramide Etodolac Felbinac Fenclozic acid Fentiazac Indomethacin Indomethacin farnesil Isoxepac Ketorolac Lonazolac Oxametacin Prodolic acid Proglumetacin Sulindac Tiopinac Tolmetin Zomepirac^†

Oxicams	Ampiroxicam Droxicam Lornoxicam Meloxicam Piroxicam Tenoxicam

Propionic acid derivatives (profens)	Alminoprofen Benoxaprofen^† Carprofen^‡ Dexibuprofen Dexketoprofen Fenbufen Fenoprofen Flunoxaprofen Flurbiprofen Ibuprofen^# Ibuproxam Indoprofen^† Ketoprofen Loxoprofen Miroprofen Naproxen Oxaprozin Pirprofen Suprofen Tarenflurbil Tepoxalin^‡ Tiaprofenic acid Vedaprofen^‡ COX-inhibiting nitric oxide donator: Naproxcinod

N-Arylanthranilic acids (fenamates)	Azapropazone Etofenamate Flufenamic acid Flunixin Meclofenamic acid Mefenamic acid Morniflumate Niflumic acid Tolfenamic acid Flutiazin

Coxibs	Apricoxib Celecoxib Cimicoxib^‡ Deracoxib^‡ Etoricoxib Firocoxib^‡ Lumiracoxib^† Mavacoxib^‡ Parecoxib Robenacoxib^‡ Rofecoxib^† Valdecoxib^†

Other	Aminopropionitrile Benzydamine Chondroitin sulfate Diacerein Fluproquazone Glucosamine Glycosaminoglycan Hyperforin Nabumetone Nimesulide Oxaceprol Proquazone Superoxide dismutase/Orgotein Tenidap

Items listed in bold indicate initially developed compounds of specific groups. ^#WHO-EM ^†Withdrawn drugs. ^‡Veterinary use medications.

Topical products for joint and muscular pain (M02)

Anti-inflammatory
preparations,
non-steroids

Pyrazolidines	Phenylbutazone Mofebutazone Clofezone Oxyphenbutazone

Acetic acid derivatives	Tolmetin Diclofenac Fentiazac

Other	Benzydamine Etofenamate Piroxicam Felbinac Bufexamac Ketoprofen Bendazac Naproxen Ibuprofen Feprazone Niflumic acid Meclofenamic acid Flurbiprofen Suxibuzone Indometacin Nifenazone

Capsaicin derivatives

Zucapsaicin

Other

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