Famprofazone
 | |
| Systematic (IUPAC) name | |
|---|---|
|
1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one | |
| Clinical data | |
| Routes of administration | Oral |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | 22881-35-2 |
| ATC code | none |
| PubChem | CID 3326 |
| ChemSpider | 3209 |
| UNII |
HN0NCX453C  |
| ChEMBL | CHEMBL1475693 |
| Chemical data | |
| Formula | C24H31N3O |
| Molar mass | 377.52 g/mol |
| |
Famprofazone (Gewodin, Gewolen) is a non-steroidal anti-inflammatory agent (NSAID) of the pyrazolone series which is available over-the-counter in some countries such as Taiwan.[1][2][3] It has analgesic, anti-inflammatory, and antipyretic effects.[1][2] Famprofazone has been known to produce methamphetamine as an active metabolite, with 15-20% of an oral dose being converted to it.[4][5] As a result, famprofazone has occasionally been implicated in causing false positives on drug tests for amphetamines.[3]
See also
References
- 1 2 Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. p. 1932. ISBN 3-88763-075-0.
- 1 2 Hall, Judith A.; Morton, Ian (1999). Concise dictionary of pharmacological agents: properties and synonyms. Kluwer Academic. p. 342. ISBN 0-7514-0499-3.
- 1 2 Chan KH, Hsu MC, Tseng CY, Chu WL (2010). "Famprofazone use can be misinterpreted as methamphetamine abuse". Journal of Analytical Toxicology 34 (6): 347–53. doi:10.1093/jat/34.6.347. PMID 20663288.
- ↑ Oh ES, Hong SK, Kang GI (March 1992). "Plasma and urinary concentrations of methamphetamine after oral administration of famprofazone to man". Xenobiotica 22 (3): 377–84. doi:10.3109/00498259209046649. PMID 1496827.
- ↑ Shin HS, Park BB, Choi SN, Oh JJ, Hong CP, Ryu H (1998). "Identification of new urinary metabolites of famprofazone in humans". Journal of Analytical Toxicology 22 (1): 55–60. doi:10.1093/jat/22.1.55. PMID 9491970.
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