Bendazac

Bendazac
Systematic (IUPAC) name
[(1-benzyl-1H-indazol-3-yl)oxy]acetic acid
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Topical
Identifiers
CAS Number 20187-55-7
ATC code M02AA11 (WHO) S01BC07 (WHO)
PubChem CID 2313
ChemSpider 2223 YesY
UNII G4AG71204O YesY
KEGG D01594 YesY
ChEBI CHEBI:31257
ChEMBL CHEMBL1089221 YesY
Chemical data
Formula C16H14N2O3
Molar mass 282.294 g/mol
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Bendazac (or bendazolic acid) is a non-steroidal anti-inflammatory drug used for joint and muscular pain.

Synthesis

Principle action is inhibition of protein denaturation.

Bendazac synthesis: BE 699226 ; G. Palazzo, U.S. Patent 3,470,194 (1967, 1969 both to Francesco Angelini).

Use of chloroacetamide in the alkylation step, followed by acid hydrolysis produces bendazac (instead of benzydamine).

See also

References



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