Sulprostone

Sulprostone

Systematic (IUPAC) name
(Z)-7-[(1R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]-N-methylsulfonylhept-5-enamide
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	60325-46-4
ATC code	G02AD05 (WHO)
PubChem	CID 5312153
ChemSpider	4471583
UNII	501Q5EQ1GM
KEGG	D02725
ChEMBL	CHEMBL284178
Chemical data
Formula	C23H31NO7S
Molar mass	465.56 g/mol
SMILES CS(=O)(=O)NC(=O)CCC/C=C\C[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](COc2ccccc2)O
InChI InChI=1S/C23H31NO7S/c1-32(29,30)24-23(28)12-8-3-2-7-11-19-20(22(27)15-21(19)26)14-13-17(25)16-31-18-9-5-4-6-10-18/h2,4-7,9-10,13-14,17,19-20,22,25,27H,3,8,11-12,15-16H2,1H3,(H,24,28)/b7-2-,14-13+/t17-,19-,20-,22-/m1/s1 Key:UQZVCDCIMBLVNR-TWYODKAFSA-N
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Sulprostone is an oxytocic.

It is an analogue of prostaglandin E2.^[1]

References

1. Tamma G, Wiesner B, Furkert J, et al. (August 2003). "The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho". Journal of Cell Science 116 (Pt 16): 3285–94. doi:10.1242/jcs.00640. PMID 12829746.