Pirprofen

Pirprofen

Systematic (IUPAC) name
2-[3-chloro-4-(2,5-dihydro-1H-pyrrol-1-yl)phenyl]propanoic acid
Identifiers
CAS Number	31793-07-4
ATC code	M01AE08 (WHO)
PubChem	CID 35935
ChemSpider	33051
UNII	T7KN291890
KEGG	D05515
ChEMBL	CHEMBL188952
Chemical data
Formula	C13H14ClNO2
Molar mass	251.70876 g/mol
SMILES O=C(O)C(c1cc(Cl)c(cc1)N2C/C=C\C2)C
InChI InChI=1S/C13H14ClNO2/c1-9(13(16)17)10-4-5-12(11(14)8-10)15-6-2-3-7-15/h2-5,8-9H,6-7H2,1H3,(H,16,17) Key:PIDSZXPFGCURGN-UHFFFAOYSA-N
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Pirprofen was a non-steroidal anti-inflammatory drug that was brought to market by Ciba-Geigy in 1982 as a treatment for arthritis and pain. Its label was restricted after adverse events arose, including some cases of fatal liver toxicity. Ciba-Geigy voluntarily withdrew the drug from the market worldwide in 1990.^[1]:223

References

1. WHO. Consolidated List of Products - Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or Not Approved by Governments, Twelfth Issue - Pharmaceuticals. United Nations - New York, 2005