Unoprostone
Unoprostone
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Systematic (IUPAC) name |
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(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl) cyclopentyl]hept-5-enoic acid |
Clinical data |
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AHFS/Drugs.com |
Micromedex Detailed Consumer Information |
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Routes of administration |
Topical (eye drops) |
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Identifiers |
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CAS Number |
120373-36-6 Y 120373-24-2 |
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ATC code |
S01EE02 (WHO) |
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PubChem |
CID 5311236 |
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ChemSpider |
4470755 N |
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UNII |
6X4F561V3W N |
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KEGG |
D08661 Y |
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ChEMBL |
CHEMBL1201407 N |
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Chemical data |
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Formula |
C22H38O5 |
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Molar mass |
382.534 g/mol |
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O=C(O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CCC(=O)CCCCCCC
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InChI=1S/C22H38O5/c1-2-3-4-5-8-11-17(23)14-15-19-18(20(24)16-21(19)25)12-9-6-7-10-13-22(26)27/h6,9,18-21,24-25H,2-5,7-8,10-16H2,1H3,(H,26,27)/b9-6-/t18-,19-,20+,21-/m1/s1 NKey:TVHAZVBUYQMHBC-SNHXEXRGSA-N N
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NY (what is this?) (verify) |
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Unoprostone (INN) is a prostaglandin analogue. Its isopropyl ester, unoprostone isopropyl, is marketed under the trade name Rescula (eyedrops, 0.15%) for the management of open-angle glaucoma and ocular hypertension.
References
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| Receptor (ligands) | DP (D2) | | |
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- Antagonists: ADC-3680
- AZD-1981
- Bay U3405
- Fevipiprant
- MK-1029
- MK-7246
- OC-459
- OC000459
- QAV-680
- Ramatroban
- Setipiprant
- TM30089
- Vidupiprant
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| EP (E2) | |
- Antagonists: AH-6809
- ONO-8130
- SC-19220
- SC-51089
- SC-51322
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- Antagonists: AH-6809
- PF-04418948
- TG 4-155
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- Antagonists: GW-627368
- L-161982
- ONO-AE3-208
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| Unsorted | |
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| FP (F2α) | |
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| IP (I2) | |
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| TP (TXA2) | |
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| Unsorted |
- Arbaprostil
- Ataprost
- Ciprostene
- Clinprost
- Cobiprostone
- Delprostenate
- Deprostil
- Dimoxaprost
- Doxaprost
- Ecraprost
- Eganoprost
- Enisoprost
- Eptaloprost
- Esuberaprost
- Etiproston
- Fenprostalene
- Flunoprost
- Froxiprost
- Lanproston
- Limaprost
- Luprostiol
- Meteneprost
- Mexiprostil
- Naxaprostene
- Nileprost
- Nocloprost
- Ornoprostil
- Oxoprostol
- Penprostene
- Pimilprost
- Piriprost
- Posaraprost
- Prostalene
- Rioprostil
- Rivenprost
- Rosaprostol
- Spiriprostil
- Tiaprost
- Tilsuprost
- Tiprostanide
- Trimoprostil
- Viprostol
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| Enzyme (inhibitors) | |
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| Others | |
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| See also: Leukotrienergics |
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