Travoprost
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| Systematic (IUPAC) name | |
|---|---|
|
propan-2-yl 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl) phenoxy]-but-1-enyl]-cyclopentyl]hept-5-enoate | |
| Clinical data | |
| Trade names | Travatan, Travoprostin is the brand name which is available in preservative free form in India by Eyekare Kilitch Ltd. |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a602027 |
| Pregnancy category |
|
| Routes of administration | Topical (eye drops) |
| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number |
157283-68-6 |
| ATC code | S01EE04 (WHO) |
| PubChem | CID 5282226 |
| IUPHAR/BPS | 7102 |
| DrugBank |
DB00287 |
| ChemSpider |
4445407 |
| UNII |
WJ68R08KX9 |
| KEGG |
D01964 |
| ChEBI |
CHEBI:746859 |
| ChEMBL |
CHEMBL1200799 |
| Chemical data | |
| Formula | C26H35F3O6 |
| Molar mass | 500.548 g/mol |
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One 2.5 ml dropperette of Alcon Travatan
Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin analog (or more specifically, an analog of prostaglandin F2α)[1][2] that works by increasing the outflow of aqueous fluid from the eyes.[3] It is also known by the brand names of Travatan and Travatan Z, manufactured by Alcon, and Travo-Z, manufactured by Micro Labs.
Side effects
Possible side effects of this medication are:
- May cause blurred vision
- May cause eyelid redness
- May permanently darken eyelashes
- May cause eye discomfort
- May eventually cause permanent darkening of the iris to brown (heterochromia)
- May cause a temporary burning sensation during use
- May cause thickening of the eyelashes
- May cause inflammation of the prostate gland, restricting urine flow (BPH)
See also
References
- ↑ Alcon Laboratories, Inc. (September 2011). "TRAVATAN - travoprost solution". DailyMed. Bethesda, MD: U.S. National Library of Medicine. Retrieved 2011-09-30.
- ↑ Alcon Laboratories, Inc. (September 2011). "TRAVATAN Z (travoprost) solution". DailyMed. Bethesda, MD: U.S. National Library of Medicine. Retrieved 2011-09-30.
- ↑ AHFS Consumer Medication Information (2011-01-01). "Travoprost Ophthalmic". MedlinePlus. Bethesda, MD: U.S. National Library of Medicine. Retrieved 2011-09-30.
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4. Sethi HS, Dhawan M, Naik MP, Gupta VS. Prostaglandin analogs in glaucoma. Astrocyte 2015;2:126-32.
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