Oxaceprol

Oxaceprol
Systematic (IUPAC) name

(4R)-1-acetyl-4-hydroxy-L-proline
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	33996-33-7^Y
ATC code	D11AX09 (WHO) M01AX24
PubChem	CID 65784
ChemSpider	59203
UNII	Q0XV76B96L^Y
KEGG	D07215^Y
ChEMBL	CHEMBL1407356
Synonyms	(2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid
Chemical data
Formula	C₇H₁₁NO₄
Molar mass	172.159 g/mol
SMILES CC(=O)N1C[C@@H](C[C@H]1C(=O)O)O
InChI InChI=1S/C7H11NO4/c1-4(9)8-3-5(10)2-6(8)7(11)12/h5-6,10H,2-3H2,1H3,(H,11,12)/t5-,6+/m1/s1 Key:BAPRUDZDYCKSOQ-RITPCOANSA-N
(verify)

Oxaceprol is an anti-inflammatory drug used in the treatment of osteoarthritis.^[1] It is derived from L-proline, a DNA-encoded amino acid. The active effect of Oxaceprol is to inhibit the adhesion and migration of white blood cells.^[2]

References

↑ Herrmann G, Steeger D, Klasser M, et al. (2000). "Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac". Clin. Rheumatol. 19 (2): 99–104. doi:10.1007/s100670050025. PMID 10791619.
↑ Clayton, James J. (August 2007), "Nutraceuticals in the Management of Osteoarthritis", Orthopedics 30 (8), retrieved 2013-06-08.

Other dermatological preparations (D11)

Medicated shampoos

Cetrimide
Cadmium compounds
Ketoconazole
Povidone-iodine
Selenium compounds
Sulfur compounds
Xenysalate

Other dermatologicals

Seborrhoeic dermatitis/dandruff	Lithium succinate Pyrithione zinc

Skin whitening/depigmenting	Hydroquinone Mequinol Monobenzone

Skin darkening/pigmenting	Afamelanotide Melanotan II

Anti-inflammatory/Immunomodulators	Oxaceprol Gamolenic acid Pimecrolimus Tacrolimus Alitretinoin

Baldness treatments	5α-Reductase inhibitors Alfatradiol Finasteride Dutasteride Saw palmetto extract Antiandrogens Spironolactone Topilutamide (fluridil) Potassium channel openers Minoxidil

Hair growth inhibitors	Eflornithine 5α-Reductase inhibitors Finasteride Antiandrogens Spironolactone Cyproterone acetate Flutamide Bicalutamide Ketoconazole

Other	Calcium gluconate Magnesium sulfate Tiratricol

Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)

Pyrazolones / Pyrazolidines	Aminophenazone Ampyrone Azapropazone Clofezone Famprofazone Feprazone Kebuzone Metamizole Mofebutazone Morazone Nifenazone Oxyphenbutazone Phenazone Phenylbutazone Propyphenazone Sulfinpyrazone Suxibuzone^‡

Salicylates	Aspirin (acetylsalicylic acid)^# Aloxiprin Benorylate Carbasalate calcium Diflunisal Dipyrocetyl Ethenzamide Guacetisal Magnesium salicylate Methyl salicylate Salsalate Salicin Salicylamide Salicylic acid (salicylate) Sodium salicylate

Acetic acid derivatives and related substances	Aceclofenac Acemetacin Alclofenac Amfenac Bendazac Bromfenac Bumadizone Bufexamac Diclofenac Difenpiramide Etodolac Felbinac Fenclozic acid Fentiazac Indomethacin Indomethacin farnesil Isoxepac Ketorolac Lonazolac Oxametacin Prodolic acid Proglumetacin Sulindac Tiopinac Tolmetin Zomepirac^†

Oxicams	Ampiroxicam Droxicam Lornoxicam Meloxicam Piroxicam Tenoxicam

Propionic acid derivatives (profens)	Alminoprofen Benoxaprofen^† Carprofen^‡ Dexibuprofen Dexketoprofen Fenbufen Fenoprofen Flunoxaprofen Flurbiprofen Ibuprofen^# Ibuproxam Indoprofen^† Ketoprofen Loxoprofen Miroprofen Naproxen Oxaprozin Pirprofen Suprofen Tarenflurbil Tepoxalin^‡ Tiaprofenic acid Vedaprofen^‡ COX-inhibiting nitric oxide donator: Naproxcinod

N-Arylanthranilic acids (fenamates)	Azapropazone Etofenamate Flufenamic acid Flunixin Meclofenamic acid Mefenamic acid Morniflumate Niflumic acid Tolfenamic acid Flutiazin

Coxibs	Apricoxib Celecoxib Cimicoxib^‡ Deracoxib^‡ Etoricoxib Firocoxib^‡ Lumiracoxib^† Mavacoxib^‡ Parecoxib Robenacoxib^‡ Rofecoxib^† Valdecoxib^†

Other	Aminopropionitrile Benzydamine Chondroitin sulfate Diacerein Fluproquazone Glucosamine Glycosaminoglycan Hyperforin Nabumetone Nimesulide Oxaceprol Proquazone Superoxide dismutase/Orgotein Tenidap

Items listed in bold indicate initially developed compounds of specific groups. ^#WHO-EM ^†Withdrawn drugs. ^‡Veterinary use medications.

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