Oxaceprol

Oxaceprol
Systematic (IUPAC) name
(4R)-1-acetyl-4-hydroxy-L-proline
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Number 33996-33-7 YesY
ATC code D11AX09 (WHO) M01AX24
PubChem CID 65784
ChemSpider 59203
UNII Q0XV76B96L YesY
KEGG D07215 YesY
ChEMBL CHEMBL1407356
Synonyms (2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid
Chemical data
Formula C7H11NO4
Molar mass 172.159 g/mol
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Oxaceprol is an anti-inflammatory drug used in the treatment of osteoarthritis.[1] It is derived from L-proline, a DNA-encoded amino acid. The active effect of Oxaceprol is to inhibit the adhesion and migration of white blood cells.[2]

References

  1. Herrmann G, Steeger D, Klasser M, et al. (2000). "Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac". Clin. Rheumatol. 19 (2): 99–104. doi:10.1007/s100670050025. PMID 10791619.
  2. Clayton, James J. (August 2007), "Nutraceuticals in the Management of Osteoarthritis", Orthopedics 30 (8), retrieved 2013-06-08.
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