Pivhydrazine

Pivhydrazine

Systematic (IUPAC) name
N'-benzyl-2,2-dimethyl-propanehydrazide
Clinical data
Routes of administration	Oral
Legal status	℞ (Prescription only)
Identifiers
CAS Number	306-19-4
ATC code	none
PubChem	CID 9375
ChemSpider	9007
ChEMBL	CHEMBL2106941
Synonyms	Angorvid, Betamezid, Neomarsilid, Pivazide, Pivhydrazine
Chemical data
Formula	C12H18N2O
Molar mass	206.28 g/mol
InChI InChI=1S/C12H18N2O/c1-12(2,3)11(15)14-13-9-10-7-5-4-6-8-10/h4-8,13H,9H2,1-3H3,(H,14,15) Key:FWWDFDMCZLOXQI-UHFFFAOYSA-N
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Pivhydrazine (BAN; trade name Tersavid), also known as pivalylbenzhydrazine and pivazide, is an irreversible and non-selective monoamine oxidase inhibitor (MAOI) of the hydrazine family. It was formerly used as an antidepressant in the 1960s, but has since been discontinued.^[1][2][3]

See also

• Hydrazine (antidepressant)

References

1. Herman, ZS; Sokola, A; Lenartowicz, H; Zieliński, M; Depta, L (May–June 1976). "The influence of antidepressive drugs on the level of acetylcholine and on the acetylcholinesterase activity in the brain of rats". Polish Journal of Pharmacology and Pharmacy 28 (4): 313–321. ISSN 0301-0244. OCLC 1586290. PMID 981020.
2. Bolton, GC; Griffiths, LA (November–December 1979). "The metabolic disposition of [14C]pivhydrazine, [14C]mebanazine, and [14C]benzylhydrazine in the rat". Drug Metabolism and Disposition: the Biological Fate of Chemicals 7 (6): 388–392. ISSN 0090-9556. OCLC 1784380. PMID 43225. Retrieved 2011-09-15.
3. Mikhaĭlova, TV; Gilev, AP; Khavronina-Gureeva, ZP (1969). "[Central effects of betamezide]". Farmakologii︠a︡ i toksikologii︠a︡. (in Russian) 32 (6): 652–656. ISSN 0014-8318. OCLC 1568906. PMID 5381593.