N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
 | |
| Names | |
|---|---|
| IUPAC name
2-Ethoxy-2H-quinoline-1-carboxylic acid ethyl ester | |
| Other names
Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate | |
| Identifiers | |
16357-59-8  | |
| Abbreviations | EEDQ |
| Jmol interactive 3D | Image |
| PubChem | 27833 |
| |
| Properties | |
| C14H17NO3 | |
| Molar mass | 247.29 g/mol |
| Melting point | 62 to 67 °C (144 to 153 °F; 335 to 340 K) |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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| Infobox references | |
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) is an irreversible dopamine-receptor antagonist.[2]
EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization.[3]
References
- ↑ 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline at Sigma-Aldrich
- ↑ Neuroscience Letters 1992, 137(2), p.265
- ↑ https://www.bachem.com/bachem/bachem/joust/index.cfm?idland=223
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