4-Methylcathinone
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Systematic (IUPAC) name | |
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2-amino-1-(p-tolyl)propan-1-one | |
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Identifiers | |
CAS Number | 6941-17-9 |
PubChem | CID 414532 |
ChemSpider | 367058 |
Chemical data | |
Formula | C10H13NO |
Molar mass | 163.1 g/mol |
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4-Methylcathinone (also known as Nor-Mephedrone, 4-MC and NSC-60487), is a stimulant drug of the cathinone chemical class that has been sold online as a designer drug.[1] It is a metabolite of the better known drug mephedrone (4-methylmethcathinone).[2][3][4]
4-Methylcathinone displays a 2.4-fold selectivity to promote monoamine release via DAT over SERT as opposed to 309-fold selectivity for cathinone.[5]
See also
References
- ↑ "nor-Mephedrone". Cayman Chemical. Retrieved 27 June 2015.
- ↑ Markus R. Meyer, Jens Wilhelm, Frank T. Peters, Hans H. Maurer (June 2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography–mass spectrometry". Analytical and Bioanalytical Chemistry 397 (3): 1225–1233. doi:10.1007/s00216-010-3636-5. PMID 20333362.
- ↑ Anders Just Pedersen, Lotte Ask Reitzel, Sys Stybe Johansen, Kristian Linnet (May 2012). "In vitro metabolism studies on mephedrone and analysis of forensic cases". Drug Testing and Analysis 5 (6): 430–438. doi:10.1002/dta.1369. PMID 22573603.
- ↑ Paul I. Dargan, Roumen Sedefov, Ana Gallegos, Dr David M. Wood (July 2011). "The pharmacology and toxicology of the synthetic cathinone mephedrone (4-methylmethcathinone)". Drug Testing and Analysis 3 (7-8): 454–463. doi:10.1002/dta.312. PMID 21755604.
- ↑ Blake A. Hutsell, Michael H. Baumann, John S. Partilla, Matthew L. Banks, Rakesh Vekariya, Richard A. Glennon, S. Stevens Negus (2015). "Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in rats". European Neuropsychopharmacology. doi:10.1016/j.euroneuro.2015.12.010. PMID 26738428.
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