4-Methylcathinone

4-Methylcathinone
Systematic (IUPAC) name
2-amino-1-(p-tolyl)propan-1-one
Clinical data
Legal status
Legal status
Identifiers
CAS Number 6941-17-9
PubChem CID 414532
ChemSpider 367058
Chemical data
Formula C10H13NO
Molar mass 163.1 g/mol

4-Methylcathinone (also known as Nor-Mephedrone, 4-MC and NSC-60487), is a stimulant drug of the cathinone chemical class that has been sold online as a designer drug.[1] It is a metabolite of the better known drug mephedrone (4-methylmethcathinone).[2][3][4]

4-Methylcathinone displays a 2.4-fold selectivity to promote monoamine release via DAT over SERT as opposed to 309-fold selectivity for cathinone.[5]

See also

References

  1. "nor-Mephedrone". Cayman Chemical. Retrieved 27 June 2015.
  2. Markus R. Meyer, Jens Wilhelm, Frank T. Peters, Hans H. Maurer (June 2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography–mass spectrometry". Analytical and Bioanalytical Chemistry 397 (3): 1225–1233. doi:10.1007/s00216-010-3636-5. PMID 20333362.
  3. Anders Just Pedersen, Lotte Ask Reitzel, Sys Stybe Johansen, Kristian Linnet (May 2012). "In vitro metabolism studies on mephedrone and analysis of forensic cases". Drug Testing and Analysis 5 (6): 430–438. doi:10.1002/dta.1369. PMID 22573603.
  4. Paul I. Dargan, Roumen Sedefov, Ana Gallegos, Dr David M. Wood (July 2011). "The pharmacology and toxicology of the synthetic cathinone mephedrone (4-methylmethcathinone)". Drug Testing and Analysis 3 (7-8): 454–463. doi:10.1002/dta.312. PMID 21755604.
  5. Blake A. Hutsell, Michael H. Baumann, John S. Partilla, Matthew L. Banks, Rakesh Vekariya, Richard A. Glennon, S. Stevens Negus (2015). "Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in rats". European Neuropsychopharmacology. doi:10.1016/j.euroneuro.2015.12.010. PMID 26738428.


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