1-Benzyl-4-(2-(diphenylmethoxy)ethyl)piperidine
ethyl)piperidine.png) | |
| Names | |
|---|---|
| IUPAC name
1-Benzyl-4-[2-(diphenylmethoxy)ethyl]piperidine | |
| Identifiers | |
174643-75-5  | |
| ChEMBL | ChEMBL338733  |
| ChemSpider | 8127716 |
| Jmol interactive 3D | Image |
| PubChem | 9952105 |
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| Properties | |
| C27H31NO | |
| Molar mass | 385.55 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
1-Benzyl-4-(2-(diphenylmethoxy)ethyl)piperidine is a stimulant of the piperidine class which acts as a potent and selective dopamine reuptake inhibitor.[1][2] It is closely related to vanoxerine and GBR-12,935, which in contrast are piperazines.
See also
References
- ↑ Dutta AK, Coffey LL, Reith ME (January 1997). "Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity". Journal of Medicinal Chemistry 40 (1): 35–43. doi:10.1021/jm960638e. PMID 9016326.
- ↑ Dutta AK, Davis MC, Fei XS, Beardsley PM, Cook CD, Reith ME (January 2002). "Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules". Journal of Medicinal Chemistry 45 (3): 654–62. doi:10.1021/jm010316x. PMID 11806716.
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