Mebhydrolin

Mebhydrolin

Systematic (IUPAC) name
5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy category	Not established[1]
Routes of administration	Oral[1]
Identifiers
CAS Number	524-81-2 6153-33-9[2]
ATC code	R06AX15 (WHO)
PubChem	CID 22530
ChemSpider	21129
UNII	9SUK9B7XVY
KEGG	D08161
Synonyms	9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-gamma-carboline, Incidal, Omeril, Diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate[3]
Chemical data
Formula	C19H20N2[4]
Molar mass	276.376 g/mol
SMILES CN3Cc4c1ccccc1n(Cc2ccccc2)c4CC3
InChI InChI=1S/C19H20N2/c1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15/h2-10H,11-14H2,1H3 Key:FQQIIPAOSKSOJM-UHFFFAOYSA-N
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Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to enhance the performance-deficit effects of alcohol.^[5]

References

1. "FABAHISTIN 50 mg (Tablets)". South African Electronic Package Inserts. September 1970. Archived from the original on October 17, 2006. Retrieved 2007-03-02.
2. "Diazoline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.
3. "Mebhydroline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.
4. "Mebhydrolin chemical information". PubChem. Retrieved 2007-03-02.
5. Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK (October 1981). "Interaction between ethanol and antihistamines: 3. mebhydrolin". Med. J. Aust. 2 (9): 477–9. PMID 6119605.