Dexchlorpheniramine

Chlorpheniramine
Systematic (IUPAC) name
(3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-3-ylpropan-1-amine
Clinical data
Trade names Chlor-trimeton
AHFS/Drugs.com monograph
MedlinePlus a682543
Routes of
administration
Oral
Legal status
Legal status
  • AU: S3 (Pharmacist only)
Identifiers
CAS Number 25523-97-1 YesY
ATC code R06AB02 (WHO)
PubChem CID 33036
IUPHAR/BPS 1210
DrugBank DB01114 YesY
ChemSpider 30576 YesY
UNII 3Q9Q0B929N YesY
KEGG D07803 YesY
ChEBI CHEBI:4464 YesY
ChEMBL CHEMBL1201353 YesY
Chemical data
Formula C16H19ClN2
Molar mass 274.788 g/mol
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Dexchlorpheniramine (trade name Polaramine) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.[1][2] It is the pharmacologically active dextrorotatory isomer of chlorpheniramine.

References

  1. Theunissen, E. L.; Vermeeren, A.; Ramaekers, J. G. (2006). "Repeated-dose effects of mequitazine, cetirizine and dexchlorpheniramine on driving and psychomotor performance". British Journal of Clinical Pharmacology 61 (1): 79–86. doi:10.1111/j.1365-2125.2005.02524.x. PMC 1884990. PMID 16390354.
  2. Ortíz San Román, L.; Sanavia Morán, E.; Campos Domínguez, M.; Peinador García, M. M. (2013). "Síndrome anticolinérgico por dexclorfeniramina como causa de retención urinaria". Anales de Pediatría 79 (6): 400–1. doi:10.1016/j.anpedi.2013.02.014. PMID 23680058.

External links

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