Phosalone

Phosalone
Names
IUPAC name
6-chloro-3-(diethoxyphosphinothioylsulfanylmethyl)-1,3-benzoxazol-2-one
Other names
Zolone
Identifiers
2310-17-0 YesY
ChEBI CHEBI:8121 YesY
ChEMBL ChEMBL1528531 N
ChemSpider 4629 YesY
Jmol interactive 3D Image
KEGG C11028 YesY
PubChem 4793
UNII 448B85HT8M YesY
Properties
C12H15ClNO4PS2
Molar mass 367.80 g·mol−1
Appearance Colorless crystaline
Odor garlic
Density 1.39 g cm−3
Melting point 47.5 to 48 °C (117.5 to 118.4 °F; 320.6 to 321.1 K)
3.05 mg/L
Solubility many organic solvents
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide. It is developed by Rhône-Poulenc in France but EU eliminated it from pesticide registration on December 2006.

The median lethal dose of oral exposure in rat is 85 mg/kg and that of dermal is 390 mg/kg.[1]。It is a weak acetylcholinesterase inhibitor.[2] It is taken by not only oral and inhalation but skin and it causes toxic symptoms peculiar to organophosphorus compounds such as miosis, hypersalivation, hyperhidrosis, chest pressure, pulmonary edema and fecal incontinence.[3] It is flammable and decomposes to toxic gases such as phosphorus oxides, sulfur oxides and nitrogen oxides.[2] It is harmful especially to water creatures.

References

  1. ↑ 製品安全データシート（安全衛生情報センター）
  2. 1 2 国際化学物質安全性カード
  3. ↑ 植村振作・河村宏・辻万千子・冨田重行・前田静夫著 (2002). 農薬毒性の事典 改訂版. 三省堂. ISBN 978-4385356044.

External links


This article is issued from Wikipedia - version of the Friday, July 31, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.