Timiperone

Timiperone
Systematic (IUPAC) name

1-(4-fluorophenyl)-4-[4-(2-sulfanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]butan-1-one
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
Legal status
Legal status	â„ž (Prescription only)
Identifiers
CAS Number	57648-21-2^Y
ATC code	none
PubChem	CID 3033151
ChemSpider	2297930^N
UNII	626DQ7N19L^Y
KEGG	D02035^Y
Chemical data
Formula	C₂₂H₂₄FN₃OS
Molar mass	397.50 g/mol
SMILES C1CN(CCC1N2C3=CC=CC=C3NC2=S)CCCC(=O)C4=CC=C(C=C4)F
InChI InChI=1S/C22H24FN3OS/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28)^N Key:YDLQKLWVKKFPII-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Timiperone is an antipsychotic of the butyrophenone class.^[1]^[2]

Based on benperidol but thiourea instead of normal urea.

References

â†‘ Pharmacological studies on timiperone, a new neuroleptic drug Part II: General pharmacological properties., Arzneimittelforschung. 1981;31(4):707-15, PMID 6113834 PubMed - indexed for MEDLINE
â†‘ Effect of Timiperone, a New Antipsychotic Drug, on the Sleep-Wakefulness Cycle in Cats, The Japanese Journal of Pharmacology, Vol.39 , No.3(1985)pp.391-394

Antipsychotics (neuroleptics) (N05A)

Typical	Benzamides Levosulpiride Sulpiride Veralipride^â€¡ Butyrophenones Aceperone Azaperone Benperidol Bromperidol Droperidol Fluanisone Haloperidol^# Lenperone Moperone Pipamperone Spiperone Timiperone Trifluperidol Diphenylbutylpiperidines Clopimozide Fluspirilene Penfluridol Pimozide Phenothiazines Acepromazine Acetophenazine Butaperazine Carphenazine Chloracizine Chlorproethazine Chlorpromazine Cyamemazine Dixyrazine Fluacizine Fluphenazine Levomepromazine/Methotrimeprazine Mesoridazine Perazine Periciazine Perphenazine Perphenazine 4-aminobutyrate Piperacetazine Pipotiazine Prochlorperazine Promazine Promethazine Propiomazine Sulforidazine Thiethylperazine Thiopropazate Thioproperazine Thioridazine Trifluoperazine Triflupromazine Thioxanthenes Chlorprothixene Clopenthixol Clothixamide Flupentixol Fluprothixene Piflutixol Teflutixol Thiothixene Zuclopenthixol Tricyclics Fluotracen Loxapine Trimipramine Others Butaclamol Prothipendyl

Atypical	Benzamides Amisulpride Nemonapride Remoxipride^â€¡ Sultopride Tiapride Butyrophenones Cinuperone Melperone Setoperone Benzo(iso)oxazole piperidines Iloperidone Ocaperidone^Â§ Paliperidone Risperidone^# Benzo(iso)thiazole piperazines Lurasidone Perospirone Revospirone^Â§ Tiospirone^Â§ Ziprasidone Diphenylbutylpiperazines Amperozide Phenylpiperazines Aripiprazole Aripiprazole lauroxil Bifeprunox^Â§ Brexpiprazole Cariprazine Tricyclics Amoxapine Asenapine Carpipramine Clocapramine Clorotepine Clotiapine Clozapine^# Fluperlapine Gevotroline Metitepine Mosapramine Olanzapine Quetiapine Tenilapine Zotepine Others Blonanserin ITI-007^â€ Molindone Pimavanserin RP5063^â€ Sertindole Zicronapine^Â§

Others	Azacyclonol Cannabidiol Oxypertine Reserpine Tetrabenazine

^#WHO-EM ^â€¡Withdrawn from market Clinical trials: ^â€Phase III ^Â§Never to phase III

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