Benzamide

Benzamide
Names
IUPAC name
Benzamide
Other names
Benzoic acid amide, Phenyl carboxamide, Benzoylamide
Identifiers
55-21-0 YesY
ChEBI CHEBI:28179 YesY
ChEMBL ChEMBL267373 YesY
ChemSpider 2241 YesY
EC Number 200-227-7
Jmol interactive 3D Image
Image
KEGG C09815 YesY
PubChem 2331
RTECS number CU8700000
UNII 6X80438640 YesY
Properties
C7H7NO
Molar mass 121.14 g·mol−1
Appearance Off-white solid
Density 1.341 g/cm3
Melting point 127 to 130 °C (261 to 266 °F; 400 to 403 K)
Boiling point 288 °C (550 °F; 561 K)
13 g/l
Acidity (pKa) 23.35 (in DMSO)
Pharmacology
ATC code N05AL
Hazards
Harmful (Xn)
R-phrases R22 R40
S-phrases S36/37/39
NFPA 704
Flammability code 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g., canola oil Health code 1: Exposure would cause irritation but only minor residual injury. E.g., turpentine Reactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g., liquid nitrogen Special hazards (white): no codeNFPA 704 four-colored diamond
1
1
0
Flash point 180 °C (356 °F; 453 K)
> 500 °C (932 °F; 773 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Benzamide is an off-white solid with the chemical formula of C6H5CONH2. It is a derivative of benzoic acid. It is slightly soluble in water, and soluble in many organic solvents.

Chemical derivatives

A number of substituted benzamides exist, including:

The sedatives trimetozine, and tricetamide, the CNS stimulants ethamivan, and nikethamide, the anthelmintic agents niclosamide, clioxanide and bromoxanide, the coccidiostat aklomide, and the antiarrhythmic agent capobenic acid are all made from the corresponding benzoic acids in obvious ways.

See also

References

  1. Singh, K. N. and Merchant, Kavita (2012). "The Agrochemical Industry, Annex 17.1". In Kent, James A. Handbook of Industrial Chemistry and Biotechnology. New York: Springer Verlag. pp. 643–698 page 693. doi:10.1007/978-1-4614-4259-2_17.

External links

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